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Projects

Stem cells and their niche in the adult mammalian brain Neural stem cells continuously generate new neurons in restricted areas of the adult mammalian brain. Adult stem cells reside in specialized niches that support their…


T cells: No time to die

Like human beings, every cell in our body tries to ward off death as long as it can. This is particular true for a specific type of immune cells, called T-lymphocytes, or T cells for short. These cells keep viruses,…


A bacterial toxin facilitating chronic infection

When pathogens invade our body the immune system is put on alert. The body’s immune cells are recruited to the site of infection and an inflammatory reaction is initiated to rapidly eliminate the invaders. Some pathogens,…


Everything in balance? How a molecular switch controls lipid metabolism

All organisms need energy to live. We get energy from various components of our food. Our body uses a part of this energy directly and stores the rest. While glucose serves as an immediately available energy source, fats are…


Projects

Cell signaling and dynamics in bacterial growth, adaptation, and persistence Our studies aim at understanding the molecular and cellular principles involved in the growth, differentiation and behavior of bacterial cells. We…


Numerous genes important for muscle-nerve connection identified

Walking, breathing, or writing – these movements would not be possible without our muscles. The instructions are given by the nerves that communicate with the muscles through neuromuscular junctions. Damage to or loss of…


Overview

Studying Biology in Basel Biology is the key science of the 21st century. The University of Basel offers a variety of degrees in biology, including a Bachelor of Science in Biology with three specializations and six…


Resistant cancer cells: 3D structure of a drug transporter decoded

In the course of evolution, the human body has developed diverse strategies to protect itself from harmful substances. In the intestine, the placenta and also in the blood-brain barrier are tiny transport proteins, which…


Biozentrum Highlights: 2021 in Review

The past year was in every respect exceptional for the Biozentrum. And so it happened that “the move” coincided with the 50th Jubilee. The kick-off was the official handover of the new building to the University of Basel. In…


Pregnancy remodels the brain: stem cells shape the sense of smell in mothers

Recognizing their offspring by smell ensures animal parents can nurture their own young. The research group led by Prof. Fiona Doetsch at the Biozentrum, University of Basel, has now demonstrated in mice that new nerve cells…