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Current Research in Bioinformatics I

Current Research in Bioinformatics I In previous studies, we have characterized the impact of subtle changes in (human) core body temperature on alternative splicing and gene expression. We have shown how a family of…


The Price of Creativity: Exploring the Art Market

Mary Wood is an experienced art consultant with over 15 years in the industry, specializing in Modern and Contemporary art. She holds a degree in Art History from the University of Texas at Austin and recently spearheaded…


Balzan Prize for Prof. Michael N. Hall from the Biozentrum

Michael N. Hall receives the Balzan Prize for his groundbreaking contributions to our understanding of the molecular mechanisms that regulate cell growth and ageing. Michael Hall discovered two proteins, TOR1 and TOR2, which…


Biozentrum spin-off Translation-X receives Venture Kick funding

The Biozentrum startup Translation-X is pioneering a precision medicine approach to address the core symptoms of autism-spectrum disorders such as social interaction difficulties. The company recently reached an important…


New target to treat severe autoimmune disease

LRBA deficiency is a rare and severe autoimmune disorder that was first described in 2012. This disease is caused by a genetic defect in the LRBA gene and is characterized by an impaired immune response and autoimmunity.…


Elucidation of Host-Pathogen Interactions lead to Antibiotic-Sparing Therapeutics

Elucidation of Host-Pathogen Interactions lead to Antibiotic-Sparing Therapeutics Urinary tract infection is a significant cause of morbidity in women throughout their lifespan, in infant boys and in older men. Serious…


Vivek Malhotra

A new pathway for collagen secretion and wound healing control The concept of receptor-mediated trafficking of secretory cargo through small coated vesicles is well established, with notable examples including clathrin,…


Bacterial traits of antibiotic treatment failures

Bacterial traits of antibiotic treatment failures Antibiotic development and treatment are based on in vitro measures of bacterial growth inhibition, with growth indicating drug resistance. Much less is known about the…


Synopsis

Synopsis Antibiotic resistance has re-emerged as a critical problem of contemporary medicine. I will discuss the biological processes contributing to the spread of antibiotic resistance. In this talk, I will ask how…


Past Pandemics and One Health: Tracing pathogen through time with ancient DNA

Past Pandemics and One Health: Tracing pathogen through time with ancient DNA Research on ancient pathogens enables us to gain new perspectives on the evolutionary history of pathogens and their adaptation to different host…