Evolution of viruses and bacteria We want to understand the dynamics of evolution and the forces that drive it. Evolution of plants and animals tend to happen over centuries of even longer time-scales. Microbial organisms,…

Pioneers The transcription factors that specific cell fates Our body consists of 30 trillion cells that are organized into organs such as the liver, heart and kidneys. These specialized cells are generated in the embryo by a…

Chromosomes in 3D The developmentally dynamic nucleus How are chromosomes organized within nuclei? And how does organization impact developmental events? The nucleus is very dynamic during embryogenesis, in part because…

Epigenetic Inheritance How moms sense the environment and inform their offspring Lamarck believed that animals could respond to their environment and pass that information to their progeny independent of gene mutations.…

Lab news University of Toronto March 2023 Big congratulations to Ahilya and Jadiel on their tenure track faculty job searches. Ahilya got 6 offers from 8 interviews, and will join the University of Toronto &…

Gallery - 2020 Absolut Mango Mango Shop Hongkong Bob Ross Paint Night – March 2019 Visiting the new Biozentrum – January 2019 Visiting the new Biozentrum – January 2019 Scavenger hunting in Basel Christmas 2018 Cookie…

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H2020-MSCA-IF Projekt AL4BIOCH Assembly Lines for Biocombinatorial Chemistry Researcher: Hugo Munoz Polyketide Synthases (PKS) are biological factories for the production of potent natural products, including antibiotics,…

Selected publications Kaur, Jakob et al , Nature 593 , 125–129 (2022) We identified the mode of action of darobactin, a natural antibiotic that inhibits the insertase BamA in Gram-negative bacteria. Darobactin binds to the…

CV of Prof. Dr. Susan Mango ORCID 0000-0002-2146-3237 Nationality : USA Positions: Since 2019 Professor of Cell and Developmental Biology, Biozentrum, University of Basel, Switzerland 2009 - 2019 Professor, Dept. of…