The coronin pathway and cell population size control T cells require the protein coronin 1 to reach and maintain their cell population size. The movie illustrates T cells dividing until their appropriate density has been…
Research Instrumentation Facility Cutting-edge research requires the ability to quickly adopt, or rapidly innovate and develop novel devices and technology - from simple mechanical gadgets to sophisticated multi-sensory…
How the brain controls sleep Sleep is essential, yet its function remains one of biology’s biggest mysteries. A short or poor night of sleep is usually followed by longer and/or deeper periods of sleep. The existence of such…
Formation and function of membraneless organelles Life ultimately depends on the tight control of gene expression, which requires ordered and efficient processing of various RNA molecules. Yet, we know very little about the…
How embryonic cells develop into complex organs Our body consists of 30 trillion cells that are organized into organs such as the liver, heart and kidneys. These specialized cells are generated in the embryo by a combination…
Nanobiology: Life signs at the nanoscale Nature has developed sophisticated biological machines that are fundamentally intriguing and technologically unprecedented. Here, we use quantitative nanoscience techniques and…
Signaling in bacterial infections Bacteria can rapidly adapt to their surroundings through the ability to sense and respond to different environmental conditions. This allows bacterial pathogens to successfully persist in…
NMR spectroscopy to unravel biomolecular mechanisms Proteins perform a wide range of essential biological functions, including signal transduction, catalysis, cellular homeostasis, metabolism and membrane transport. We…
Understanding biomolecular function All biological processes, for example cell division, infection or development of cancer, are based on specific interactions between biomolecules. These interactions are consequences of the…
How bacterial pathogens establish chronic infection Infectious diseases of bacterial origin are a growing problem in today's society. The reasons for this are the increasing emergence of antibiotic resistant organisms, the…
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