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Research Fields

Research Fields Research at the Biozentrum is dedicated to the central question of how molecules and cells create life. We study the physical and biochemical mechanisms of cells and explore the behaviors and dynamics of…


Host tissue responses to bacterial infection: A story of Mice and Men

Host tissue responses to bacterial infection: A story of Mice and Men Bacterial infection takes place in the complex microenvironment of the host tissue. Dependent on the infection type, this environment varies dramatically…


Characterizing bacterial behavior during human infection to guide new discoveries

Characterizing bacterial behavior during human infection to guide new discoveries Bacterial behavior and physiology during human infection is difficult to study and largely unknown, as our vast knowledge of infection…


Bacterial effectors and their many ways to modulate immune signaling

Bacterial effectors and their many ways to modulate immune signaling Many Gram-negative bacteria modulate host immune responses through the activity of effector proteins delivered by secretion systems. The downstream changes…


Second round for the National Center of Competence in Research “AntiResist”

The extension of the program followed an evaluation by the Swiss National Science Foundation (SNSF). The assessment of the NCCR AntiResist , a program marked by its innovative, multidisciplinary approach to antibiotic…


The power of neighbors: Neighboring synapses shape learning and memory

In 1949, the Canadian psychologist Donald O. Hebb described that connections between neurons become stronger when the neurons are active at the same time, and that strengthened connections facilitate signal transmission. The…


Apply now! Biozentrum PhD Fellowships

"The Biozentrum is an institute that has always attracted good researchers. By providing the Biozentrum PhD Fellowships program, we also have a unique tool to actively recruit outstanding, international junior scientists,"…


Two Biozentrum researchers selected as International Society for Computational Biology Fellow

Prof. Torsten Schwede The ICSB honors Torsten Schwede, Professor of Structural Bioinformatics at the Biozentrum and Vice President for Research of the University of Basel, for his substantial contributions to computational…


Sleep-wake rhythm: Fish change our understanding of sleep regulation

Until recently, it was assumed that vertebrates share similar mechanisms controlling sleep behavior. That's why researchers have been using fish in the past 20 years as a model organism to study sleep and its regulation. Now…


DNA transfer by conjugation in live-cells

DNA transfer by conjugation in live-cells DNA conjugation is a contact-dependent horizontal gene transfer mechanism responsible for the dissemination of metabolic properties in bacteria, including drug resistance. Despite…