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Uncovering lung injury mechanisms in COVID-19-induced ARDS using single-cell genomics

Uncovering lung injury mechanisms in COVID-19-induced ARDS using single-cell genomics The mechanistic basis of lung injury induced by SARS-CoV-2 remains poorly understood. In the most severe COVID-19 cases, patients develop…


Long read sequencing: From research to clinical

Long read sequencing: From research to clinical Understanding the mechanism behind human diseases with an established heritable component is the next frontier in personalized medicine. Furthermore, understanding how these…


Long read sequencing: From research to clinical

Long read sequencing: From research to clinical Understanding the mechanism behind human diseases with an established heritable component is the next frontier in personalized medicine. Furthermore, understanding how these…


Mucosal immunity in the bladder

Mucosal immunity in the bladder Urinary tract infections (UTI) are the second most common infection, impacting nearly 50% of all women. Indeed, otherwise healthy, premenopausal women have a significantly greater incidence of…


In good times and bad: how chromatin communicates with the circadian clock

In good times and bad: how chromatin communicates with the circadian clock The circadian clock, a conserved gene-regulatory network, drives rhythmic daily expression of thousands of RNAs in nearly all mammalian tissues to…


Cholera bacteria form aggressive biofilm to kill immune cells

Many bacteria adopt a fascinating defense strategy by forming communities on surfaces, known as biofilms. We encounter such biofilms in our daily lives, for example, as dental plaque in the mouth, slimy films on stones in…


Obituary for Walter Keller (1938 - 2023)

On March 30th, 2023, Prof. em. Walter Keller passed away at the age of 84 years in Basel, after a long illness. With his death, the Biozentrum has lost an outstanding scientist, an important figure in shaping the institute…


«We need to learn how to deal with AI tools like ChatGPT because they will not disappear.»

Did the development of an artificial intelligence (AI) tool like ChatGPT surprise you personally? I think we were all surprised by the rapid pace of this development and above all by the quality and versatility of this chat…