D1: Molecular and Cellular Structural Biology I  – 12421

(2 hrs/week; 2 CP; Fall 2024)

Stephan Grzesiek, Michael Hennig, Timm Maier

This course will provide an overview of the forces and interactions that stabilize biological macromolecules. The role of these interactions for the structure and stability of peptides, proteins and DNA will be discussed. Topics include molecular geometries, electrostatic interactions, hydrogen bonding, van der Waals interactions, solvation effects, molecular dynamics, and structure prediction.