Synthetic Microbiology – 12469
(Block Course / 3 weeks, 8 CP; Fall 2022)
→ 1-2 students could take part, depending on space availability. If you are interested, please contact A. Becskei.
The course covers concepts of synthetic gene regulatory networks in microorganisms. The relevant molecular biological mechanisms are discussed, followed by the kinetic description of these mechanisms. Subsequently, experiments are performed that demonstrate network behavior including cellular memory, bell-shaped response and stochastic gene expression. By the ends of the course, the students will be able to write up, solve and analyze basic equations describing gene regulatory mechanisms. Furthermore, students will be able to construct synthetic gene regulatory networks for specific behaviors.