Research Projects Biophysical Principles of Chaperone Function Molecular chaperones play a key role in cellular processes, including protein homeostasis, but also in membrane protein transport and biogenesis. We employ…

Structure, function, and evolution of genome-wide regulatory networks Most projects that we pursue concern the functioning and evolution of genome-wide regulatory systems in organisms ranging from bacteria to humans. The…

How the brain controls sleep Sleep is essential, yet its function remains one of biology’s biggest mysteries. A short or poor night of sleep is usually followed by longer and/or deeper periods of sleep. The existence of such…