G protein-coupled receptors are embedded in the cell membrane and transmit signals from the outside to the inside of the cell. Because of their vast diversity and crucial role in the body, GPCRs are targeted by many drugs,…
Misfolded proteins are non-functional and cause cell damage. In order to prevent this, there is a whole arsenal of proteins – called chaperones – that assist with folding and carry out quality control. In the bacterium…
Autism occurs in about one percent of the population and is characterized by alterations in communication, repetitive behavior and social difficulties. There are numerous genetic factors involved in the development of…
Our body is made up of a wide variety of cells with the most diverse functions. Irrespective of being heart, liver or nerve cells, however, they all contain the same genetic information. The reason why cells develop…
Throughout our body there is a dense, widely ramified network of blood vessels. It is estimated to be about 150,000 kilometers in length. The vessels supply all cells, even those in most far away regions of the body with…
There is talk about Omicron being the beginning of the end and the start of an endemic situation. What exactly does that mean? If the pandemic becomes endemic, it means that a certain balance is established between the virus…
Muscular dystrophy is a term used to describe many different muscular diseases caused by genetic defects. To date, there are no treatments available to stop disease progression. In their study, the scientists led by Prof.…
Cell signalling and cell rearrangement during organ morphogenesis The organization of body pattern in developing multi-cellular organisms is controlled to a large extent by cell-cell signaling. In the past two decades, the…
Antibiotics are still the treatment of choice in fighting bacterial infections. However, due to their extensive and sometimes improper use in medicine and livestock farming, resistant pathogens are increasingly emerging,…
Be it through mucosa or the intestinal lining, different tissues and surfaces of our body are entry gates for bacterial pathogens. The first few seconds - the moment of touch - are often critical for successful infections.…
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