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How neuromuscular connections are maintained after nerve lesions

The protein complex mTORC1 promotes muscle growth and is important for the self-cleaning process of the muscle cells. The role of mTORC1 in skeletal muscle fibers in response to nerve injury has so far not been studied in…


Reaching and Grasping – Learning fine motor coordination changes the brain

Simply grasping a coffee cup needs fine motor coordination with the highest precision. This required performance of the brain is an ability that can also be learned and trained. Prof. Kelly Tan's research group at the…


T3 Pharmaceuticals awarded highest endowed startup prize

T3 Pharmaceuticals is one of top five startup companies selected by the W.A. de Vigier Foundation. The winning companies were selected from a record number of 256 applications in a multi-step process. At the award ceremony…


Treating muscular disease – Santhera and Biozentrum join forces

Santhera Pharmaceuticals has started a collaboration with Prof. Markus Rüegg, who pioneered a novel gene therapy approach for the treatment of type 1 congenital muscular dystrophy (MDC1A). MDC1A is a severe form of…


Relay station in the brain controls our movements

Whether we move our arms, legs or the entire body, every movement is centrally controlled by our brain. Different brain regions and neuronal networks play an essential role in this process. This includes the Substantia…


Crime Scene Schizophrenia - 30 Genes under suspicion

The research team led by Prof. Alex Schier, Director of the Biozentrum, University of Basel, and currently group leader at Harvard University in Cambridge, investigated a total of 132 genes associated with schizophrenia. The…


ERC Advanced Grant for Alex Schier

The ERC Advanced Grants, which are awarded by the European Research Council (ERC), are among the most prestigious and coveted grants in basic research: only 10 percent of application submissions are successful. The grants…


Molecular bodyguards against Parkinson's disease

Parkinson's disease is one of the most common neurodegenerative disorders. In Switzerland, about 15,000 people are affected. Because of the worldwide rise in life expectancy, a rapid increase in Parkinson's cases is expected…


Biozentrum spin off ARTIDIS raised 8.8 Million Swiss Francs

“The closure of this financing round and the successful recruitment of 545 patients in our first clinical study at the University Hospital Basel this year is a huge success”, states Marija Plodinec, CEO of ARTIDIS. “We are…


Magnesium deprivation stops pathogen growth

When pathogens infect an organism, the defense system immediately starts to fight the bacteria. To escape the patrolling immune cells, some bacteria invade and replicate inside host cells. However, the host has developed…