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Uropathogenic Escherichia coli (UPEC) and Urinary Tract Infections (UTIs)

Uropathogenic Escherichia coli (UPEC) and urinary tract infections (UTIs) Deciphering UPEC in-vivo physiology To truly understand how UPEC behave inside the human bladder, we go straight to the source – analyzing urine…


Lab-on-a-chip for tracking single bacterial cells

It is hardly bigger than a matchbox and yet there is a laboratory en miniature on this chip. Single bacterial cells grow in about 2000 channels of a thousandth of a millimeter in diameter and can be individually studied in…


New vaccine concept tackles harmful bacteria in the intestine

The issue of intestinal bacteria is a complex one. On the one hand, we are dependent on the microorganisms because they are the ones that digest the food in our intestine. On the other hand, there are also numerous pathogens…


Projects

Regulation of skeletal muscle cell plasticity in health and disease Skeletal muscle has an enormous capacity to adapt to external stimuli including physical activity, oxygen levels, ambient temperature, nutrient availability…


Cell Biology Lecture Series

Cell Biology Lecture Series The "Cell Biology Lecture Series" is a joint effort of the Research Groups Engel, Hall, Hondele, Keller, Rüegg, Schier and Spang to monthly host international speakers to talk about current…


Highlights 1971 - 2021

Biozentrum Highlights 1971 - 2021 1968 − Pioneering concept The potential of molecular biology was recognized early in Switzerland – in the 1960s. Due to the visionary leadership of Arnold Schneider, a member of the Cantonal…


Sophisticated swarming: Bacteria support each other across generations

In nature, bacteria usually live in communities. They collectively colonize our gut, also known as the gut microbiome, or form biofilms such as dental plaque. Living in communities provides many advantages to the individual…


Rapid fluctuations drive complex gene regulation in bacteria

Bacteria may be small, but they have a remarkable ability to adapt. They colonize a wide variety of habitats – from the human gut to hot springs – and respond with great flexibility to changes in their environment. One…