We study the cellular organization and regulation of metabolism by large macromolecular assemblies as well as giant microbial biosynthetic assembly lines. Our research builds on hybrid use of state-of-the-art cryo electron…
Research Projects Biophysical Principles of Chaperone Function Molecular chaperones play a key role in cellular processes, including protein homeostasis, but also in membrane protein transport and biogenesis. We employ…
NMR spectroscopy to unravel biomolecular mechanisms Proteins perform a wide range of essential biological functions, including signal transduction, catalysis, cellular homeostasis, metabolism and membrane transport. We…
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