Interested in joining the Hiller group? We are always looking for motivated, talented and creative new team members, so if you are interested to join us, please inquire about opportunities in the lab. Postdoctoral candidates…
Pseudocontact Shifts in Biomolecular NMR Spectroscopy Thomas Müntener, Daniel Joss, Daniel Häussinger*, and Sebastian Hiller* Paramagnetic centers in biomolecules, such as specific metal ions that are bound to a protein,…
The structure of a protein reveals a lot about its function. This means, the more precisely the three-dimensional protein structure is known, the better the conclusions on its function can be drawn. Using NMR spectroscopy,…
Cells proliferate by dividing repeatedly. Each cell division produces two daughter cells, which must first grow to a certain size before they can divide, too. This requires an increased production of cell components,…
The WHO calls the creeping and rapidly growing number of antibiotic-resistant bacteria a “silent pandemic”. The crisis is aggravated by the fact that hardly any new drugs have come onto the market in recent decades. Even…
Misfolded proteins are non-functional and cause cell damage. In order to prevent this, there is a whole arsenal of proteins – called chaperones – that assist with folding and carry out quality control. In the bacterium…
Parkinson's disease is one of the most common neurodegenerative disorders. In Switzerland, about 15,000 people are affected. Because of the worldwide rise in life expectancy, a rapid increase in Parkinson's cases is expected…
The opening of the new Swiss High-field NMR Facility was attended by high-ranking representatives of the three participating universities, invited guests from academia and industry along with scientists working in the fields…
A number of pathogens protect themselves with an outer membrane that makes it difficult to combat them with antibiotics. In addition, the widespread use of antibiotics promotes the development of resistant bacteria. In…
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