NMJ maintenance and remodeling The neuromuscular junction (NMJ) is a chemical synapse that transmits motor neuron action potentials into muscle fiber action potentials (see Figure below). Without this connection, muscle…

Comparative genomics at scale in the post-AlphaFold era Within a decade, various consortia under the Earth BioGenome umbrella aim to sequence 1.5M eukaryotes. All these genomes are connected through life’s common origin, yet…

Molecular Medicine, Physiology, Metabolism and Aging Prof. Dirk Bumann Single-cell pathogen activities during infection and treatment Prof. Christoph Dehio Molecular mechanisms of chronic bacterial infections Prof. Fiona…

Technology Ventures The primary goal of the basic research investigations in molecular and biomedical biology at the Biozentrum is to investigate central questions about the smallest unit of life, the cell, as well as vital…

Structural Biology, Biochemistry and Biophysics Prof. Jan Pieter Abrahams Uncovering the fundamental shapes of life Prof. Marek Basler Unraveling the secrets of bacterial injection needles Prof. Christoph Dehio Molecular…

Photos Group photo - April 2025 Group photo - April 2025 Lab picture - Sept 2023 Lab Hike to the Creux du Van - October 2022 Lab outing in Engelberg - April 2022 Lab outing - December 2021 Group Photo Outside the New…

The cross-border commuter May 2017 Borders are not an obstacle for her, they exist to be crossed. Kathrin Thedieck has lived at open borders since her childhood. This has shaped her self-image as a European. The fact that…

BD LSR Fortessa Laser (Excitation) PMT LP Mirror BP Filter Fluorochromes Blue Laser 488nm A B C D 670 525 505 / 685/35 542/27 512/25 488/10 PerCP YFP GFP, FITC, Alexa Fluor 488 SSC Red Laser 640nm A B C 750 690 / 780/60…

Multicellular Dynamics Prof. Markus Affolter Development of blood vessels and complex organs Prof. Silvia Arber Motor circuit function Prof. David Brückner Physical principles of living systems Prof. Dirk Bumann Single-cell…

The incidence of liver cancer, also known as hepatocellular carcinoma, is steadily increasing. In the last twenty years, the number of cases has almost doubled in Switzerland. Hepatocellular carcinoma is usually diagnosed at…