Navigation mit Access Keys

Main Content

Publications

Shafer, M. E. R., Sawh, A. N. and Schier, A. F. (2021) ‘Gene family evolution underlies cell type diversification in the hypothalamus of teleosts’. bioRxiv. 10.1101/2020.12.13.414557.   edoc
Lord, N. D., Carte, A. N., Abitua, P. B. and Schier, A. F. (2021) ‘The pattern of nodal morphogen signaling is shaped by co-receptor expression’, eLife, 10, p. 54894. 10.7554/eLife.54894.   edoc | Open Access
Schier, A. F. (2020) ‘Single-cell biology: beyond the sum of its parts’, Nature Methods, 17(1), pp. 17–20. 10.1038/s41592-019-0693-3.   edoc
Raj, B., Farrell, J. A., Liu, J., El Kholtei, J., Carte, A. N., Navajas Acedo, J., Du, L. Y., McKenna, A., Relić, Đorđe, Leslie, J. M. and Schier, A. F. (2020) ‘Emergence of Neuronal Diversity during Vertebrate Brain Development’, Neuron, 108(6), pp. 1058–1074.e6. 10.1016/j.neuron.2020.09.023.   edoc | Open Access
Lin, Q., Manley, J., Helmreich, M., Schlumm, F., Li, J. M., Robson, D. N., Engert, F., Schier, A., Nöbauer, T. and Vaziri, A. (2020) ‘Cerebellar Neurodynamics Predict Decision Timing and Outcome on the Single-Trial Level’, Cell, 180(3), pp. 536–551.e17. 10.1016/j.cell.2019.12.018.   edoc
Ma, M., Ramirez, A. D., Wang, T., Roberts, R. L., Harmon, K. E., Schoppik, D., Sharma, A., Kuang, C., Goei, S. L., Gagnon, J. A., Zimmerman, S., Tsai, S. Q., Reyon, D., Joung, J. K., Aksay, E. R. F., Schier, A. F. and Pan, Y. A. (2020) ‘Zebrafish dscaml1 Deficiency Impairs Retinal Patterning and Oculomotor Function’, Journal of Neuroscience, 40(1), pp. 143–158. 10.1523/JNEUROSCI.1783-19.2019.   edoc
Lord, N. D., Carte, A. N., Abitua, P. B. and Schier, A. F. (2019) ‘The pattern of nodal morphogen signaling is shaped by co-receptor expression’, BioRxiv. Cold Spring Harbor Laboratory. 10.1101/2019.12.30.891101.   edoc
Randlett, O., Haesemeyer, M., Forkin, G., Shoenhard, H., Schier, A. F., Engert, F. and Granato, M. (2019) ‘Distributed Plasticity Drives Visual Habituation Learning in Larval Zebrafish’, Current biology : CB, 29(8), pp. 1337–1345.e4. 10.1016/j.cub.2019.02.039.   edoc
Wee, C. L., Nikitchenko, M., Wang, W.-C., Luks-Morgan, S. J., Song, E., Gagnon, J. A., Randlett, O., Bianco, I. H., Lacoste, A. M. B., Glushenkova, E., Barrios, J. P., Schier, A. F., Kunes, S., Engert, F. and Douglass, A. D. (2019) ‘Zebrafish oxytocin neurons drive nocifensive behavior via brainstem premotor targets’, Nature neuroscience, 22(9), pp. 1477–1492. 10.1038/s41593-019-0452-x.   edoc
Thyme, S. B., Pieper, L. M., Li, E. H., Pandey, S., Wang, Y., Morris, N. S., Sha, C., Choi, J. W., Herrera, K. J., Soucy, E. R., Zimmerman, S., Randlett, O., Greenwood, J., McCarroll, S. A. and Schier, A. F. (2019) ‘Phenotypic Landscape of Schizophrenia-Associated Genes Defines Candidates and Their Shared Functions’, Cell, 177(2), pp. 478–491.e20. 10.1016/j.cell.2019.01.048.   edoc
Goudarzi, M., Berg, K., Pieper, L. M. and Schier, A. F. (2019) ‘Individual long non-coding RNAs have no overt functions in zebrafish embryogenesis, viability and fertility’, eLife, 8, p. 8:e40815. 10.7554/eLife.40815.   edoc
Haesemeyer, M., Schier, A. F. and Engert, F. (2019) ‘Convergent Temperature Representations in Artificial and Biological Neural Networks’, Neuron, 103(6), pp. 1123–1134.e6. 10.1016/j.neuron.2019.07.003.   edoc
Raj, B., Gagnon, J. A. and Schier, A. F. (2018) ‘Large-scale reconstruction of cell lineages using single-cell readout of transcriptomes and CRISPR-Cas9 barcodes by scGESTALT’, Nature protocols, 13(11), pp. 2685–2713. 10.1038/s41596-018-0058-x.   edoc
Montague, T. G., Gagnon, J. A. and Schier, A. F. (2018) ‘Conserved regulation of Nodal-mediated left-right patterning in zebrafish and mouse’, Development (Cambridge, England), 145(24), p. 9. 10.1242/dev.171090.   edoc
Haesemeyer, M., Robson, D. N., Li, J. M., Schier, A. F. and Engert, F. (2018) ‘A Brain-wide Circuit Model of Heat-Evoked Swimming Behavior in Larval Zebrafish’, Neuron, 98(4), pp. 817–831.e6. 10.1016/j.neuron.2018.04.013.   edoc
Almuedo-Castillo, M., Bläßle, A., Mörsdorf, D., Marcon, L., Soh, G. H., Rogers, K. W., Schier, A. F. and Müller, P. (2018) ‘Scale-invariant patterning by size-dependent inhibition of Nodal signalling’, Nature cell biology, 20(9), pp. 1032–1042. 10.1038/s41556-018-0155-7.   edoc
Raj, B., Wagner, D. E., McKenna, A., Pandey, S., Klein, A. M., Shendure, J., Gagnon, J. A. and Schier, A. F. (2018) ‘Simultaneous single-cell profiling of lineages and cell types in the vertebrate brain’, Nature biotechnology, 36(5), pp. 442–450. 10.1038/nbt.4103.   edoc
Farrell, J. A., Wang, Y., Riesenfeld, S. J., Shekhar, K., Regev, A. and Schier, A. F. (2018) ‘Single-cell reconstruction of developmental trajectories during zebrafish embryogenesis’, Science (New York, N.Y.), 360(6392), p. 6. 10.1126/science.aar3131.   edoc
Gagnon, J. A., Obbad, K. and Schier, A. F. (2018) ‘The primary role of zebrafish nanog is in extra-embryonic tissue’, Development (Cambridge, England), 145(1), p. 9. 10.1242/dev.147793.   edoc
Pandey, S., Shekhar, K., Regev, A. and Schier, A. F. (2018) ‘Comprehensive Identification and Spatial Mapping of Habenular Neuronal Types Using Single-Cell RNA-Seq’, Current biology : CB, 28(7), pp. 1052–1065.e7. 10.1016/j.cub.2018.02.040.   edoc
Rogers, K. W., Lord, N. D., Gagnon, J. A., Pauli, A., Zimmerman, S., Aksel, D. C., Reyon, D., Tsai, S. Q., Joung, J. K. and Schier, A. F. (2017) ‘Nodal patterning without Lefty inhibitory feedback is functional but fragile’, eLife, 6, p. 6:e28785. 10.7554/eLife.28785.   edoc
Rabani, M., Pieper, L., Chew, G.-L. and Schier, A. F. (2017) ‘A Massively Parallel Reporter Assay of 3’ UTR Sequences Identifies In Vivo Rules for mRNA Degradation’, Molecular Cell, 68(6), pp. 1083–1094.e5. 10.1016/j.molcel.2017.11.014.   edoc
Norris, M. L., Pauli, A., Gagnon, J. A., Lord, N. D., Rogers, K. W., Mosimann, C., Zon, L. I. and Schier, A. F. (2017) ‘Toddler signaling regulates mesodermal cell migration downstream of Nodal signaling’, eLife, 6, p. 6:e22626. 10.7554/eLife.22626.   edoc
Montague, T. G. and Schier, A. F. (2017) ‘Vg1-Nodal heterodimers are the endogenous inducers of mesendoderm’, eLife, 6, p. 6:e28183. 10.7554/eLife.28183.   edoc
Schoppik, D., Bianco, I. H., Prober, D. A., Douglass, A. D., Robson, D. N., Li, J. M. B., Greenwood, J. S. F., Soucy, E., Engert, F. and Schier, A. F. (2017) ‘Gaze-Stabilizing Central Vestibular Neurons Project Asymmetrically to Extraocular Motoneuron Pools’, The Journal of Neuroscience, 37(47), pp. 11353–11365. 10.1523/JNEUROSCI.1711-17.2017.   edoc
Escamilla, C. O., Filonova, I., Walker, A. K., Xuan, Z. X., Holehonnur, R., Espinosa, F., Liu, S., Thyme, S. B., López-García, I. A., Mendoza, D. B., Usui, N., Ellegood, J., Eisch, A. J., Konopka, G., Lerch, J. P., Schier, A. F., Speed, H. E. and Powell, C. M. (2017) ‘Kctd13 deletion reduces synaptic transmission via increased RhoA’, Nature, 551(7679), pp. 227–231. 10.1038/nature24470.   edoc
Hildebrand, D. G. C., Cicconet, M., Torres, R. M., Choi, W., Quan, T. M., Moon, J., Wetzel, A. W., Scott Champion, A., Graham, B. J., Randlett, O., Plummer, G. S., Portugues, R., Bianco, I. H., Saalfeld, S., Baden, A. D., Lillaney, K., Burns, R., Vogelstein, J. T., Schier, A. F., Lee, W.-C. A., Jeong, W.-K., Lichtman, J. W. and Engert, F. (2017) ‘Whole-brain serial-section electron microscopy in larval zebrafish’, Nature, 545(7654), pp. 345–349. 10.1038/nature22356.   edoc
Freyer, L., Hsu, C.-W., Nowotschin, S., Pauli, A., Ishida, J., Kuba, K., Fukamizu, A., Schier, A. F., Hoodless, P. A., Dickinson, M. E. and Hadjantonakis, A.-K. (2017) ‘Loss of Apela Peptide in Mice Causes Low Penetrance Embryonic Lethality and Defects in Early Mesodermal Derivatives’, Cell reports, 20(9), pp. 2116–2130. 10.1016/j.celrep.2017.08.014.   edoc
Thyme, S. B., Akhmetova, L., Montague, T. G., Valen, E. and Schier, A. F. (2016) ‘Internal guide RNA interactions interfere with Cas9-mediated cleavage’, Nature communications, 7, p. 11750. 10.1038/ncomms11750.   edoc
Chew, G.-L., Pauli, A. and Schier, A. F. (2016) ‘Conservation of uORF repressiveness and sequence features in mouse, human and zebrafish’, Nature communications, 7, p. 11663. 10.1038/ncomms11663.   edoc
McKenna, A., Findlay, G. M., Gagnon, J. A., Horwitz, M. S., Schier, A. F. and Shendure, J. (2016) ‘Whole-organism lineage tracing by combinatorial and cumulative genome editing’, Science (New York, N.Y.), 353(6298), p. aaf7907. 10.1126/science.aaf7907.   edoc
Thyme, S. B. and Schier, A. F. (2016) ‘Polq-Mediated End Joining Is Essential for Surviving DNA Double-Strand Breaks during Early Zebrafish Development’, Cell reports, 15(4), pp. 707–714. 10.1016/j.celrep.2016.03.072.   edoc
Dunn, T. W., Mu, Y., Narayan, S., Randlett, O., Naumann, E. A., Yang, C.-T., Schier, A. F., Freeman, J., Engert, F. and Ahrens, M. B. (2016) ‘Brain-wide mapping of neural activity controlling zebrafish exploratory locomotion’, eLife, 5, p. e12741. 10.7554/eLife.12741.   edoc
Li-Villarreal, N., Forbes, M. M., Loza, A. J., Chen, J., Ma, T., Helde, K., Moens, C. B., Shin, J., Sawada, A., Hindes, A. E., Dubrulle, J., Schier, A. F., Longmore, G. D., Marlow, F. L. and Solnica-Krezel, L. (2016) ‘Dachsous1b cadherin regulates actin and microtubule cytoskeleton during early zebrafish embryogenesis’, Development, 143(10), p. 1832. 10.1242/dev.138859.   edoc
Chiu, C. N., Rihel, J., Lee, D. A., Singh, C., Mosser, E. A., Chen, S., Sapin, V., Pham, U., Engle, J., Niles, B. J., Montz, C. J., Chakravarthy, S., Zimmerman, S., Salehi-Ashtiani, K., Vidal, M., Schier, A. F. and Prober, D. A. (2016) ‘A Zebrafish Genetic Screen Identifies Neuromedin U as a Regulator of Sleep/Wake States’, Neuron, 89(4), pp. 842–856. 10.1016/j.neuron.2016.01.007.   edoc
Li-Villarreal, N., Forbes, M. M., Loza, A. J., Chen, J., Ma, T., Helde, K., Moens, C. B., Shin, J., Sawada, A., Hindes, A. E., Dubrulle, J., Schier, A. F., Longmore, G. D., Marlow, F. L. and Solnica-Krezel, L. (2015) ‘Dachsous1b cadherin regulates actin and microtubule cytoskeleton during early zebrafish embryogenesis’, Development, 142(15), pp. 2704–2718. 10.1242/dev.119800.   edoc
Dubrulle, J., Jordan, B. M., Akhmetova, L., Farrell, J. A., Kim, S.-H., Solnica-Krezel, L. and Schier, A. F. (2015) ‘Response to Nodal morphogen gradient is determined by the kinetics of target gene induction’, eLife, 4, p. e05042. 10.7554/eLife.05042.   edoc
Pauli, A., Valen, E. and Schier, A. F. (2015) ‘Identifying (non-)coding RNAs and small peptides: challenges and opportunities’, BioEssays : news and reviews in molecular, cellular and developmental biology, 37(1), pp. 103–112. 10.1002/bies.201400103.   edoc
Haesemeyer, M. and Schier, A. F. (2015) ‘The study of psychiatric disease genes and drugs in zebrafish’, Current Opinion in Neurobiology, 30, pp. 122–130. 10.1016/j.conb.2014.12.002.   edoc
Rogers, K. W., Blässle, A., Schier, A. F. and Müller, P. (2015) ‘Measuring protein stability in living zebrafish embryos using fluorescence decay after photoconversion (FDAP)’, Journal of visualized experiments, (95), p. e52266. 10.3791/52266.   edoc
Merkle, F. T., Maroof, A., Wataya, T., Sasai, Y., Studer, L., Eggan, K. and Schier, A. F. (2015) ‘Generation of neuropeptidergic hypothalamic neurons from human pluripotent stem cells’, Development (Cambridge, England), 142(4), pp. 633–643. 10.1242/dev.117978.   edoc
Pauli, A., Montague, T. G., Lennox, K. A., Behlke, M. A. and Schier, A. F. (2015) ‘Antisense Oligonucleotide-Mediated Transcript Knockdown in Zebrafish’, PloS one, 10(10), p. e0139504. 10.1371/journal.pone.0139504.   edoc
Mundell, N. A., Beier, K. T., Pan, Y. A., Lapan, S. W., Göz Aytürk, D., Berezovskii, V. K., Wark, A. R., Drokhlyansky, E., Bielecki, J., Born, R. T., Schier, A. F. and Cepko, C. L. (2015) ‘Vesicular stomatitis virus enables gene transfer and transsynaptic tracing in a wide range of organisms’, Journal of Comparative Neurology, 523(11), pp. 1639–1663. 10.1002/cne.23761.   edoc
Liu, J., Merkle, F. T., Gandhi, A. V., Gagnon, J. A., Woods, I. G., Chiu, C. N., Shimogori, T., Schier, A. F. and Prober, D. A. (2015) ‘Evolutionarily conserved regulation of hypocretin neuron specification by Lhx9’, Development, 142(6), pp. 1113–1124. 10.1242/dev.117424.   edoc
Satija, R., Farrell, J. A., Gennert, D., Schier, A. F. and Regev, A. (2015) ‘Spatial reconstruction of single-cell gene expression data’, Nature biotechnology, 33(5), pp. 495–502. 10.1038/nbt.3192.   edoc
Merkle, F. T., Neuhausser, W. M., Santos, D., Valen, E., Gagnon, J. A., Maas, K., Sandoe, J., Schier, A. F. and Eggan, K. (2015) ‘Efficient CRISPR-Cas9-mediated generation of knockin human pluripotent stem cells lacking undesired mutations at the targeted locus’, Cell Reports , 11(6), pp. 875–883. 10.1016/j.celrep.2015.04.007.   edoc
Lacoste, A. M. B., Schoppik, D., Robson, D. N., Haesemeyer, M., Portugues, R., Li, J. M., Randlett, O., Wee, C. L., Engert, F. and Schier, A. F. (2015) ‘A convergent and essential interneuron pathway for Mauthner-cell-mediated escapes’, Current biology : CB, 25(11), pp. 1526–1534. 10.1016/j.cub.2015.04.025.   edoc
Haesemeyer, M., Robson, D. N., Li, J. M., Schier, A. F. and Engert, F. (2015) ‘The structure and timescales of heat perception in larval zebrafish’, Cell Systems, 1(5), pp. 338–348. 10.1016/j.cels.2015.10.010.   edoc
Randlett, O., Wee, C. L., Naumann, E. A., Nnaemeka, O., Schoppik, D., Fitzgerald, J. E., Portugues, R., Lacoste, A. M. B., Riegler, C., Engert, F. and Schier, A. F. (2015) ‘Whole-brain activity mapping onto a zebrafish brain atlas’, Nature Methods, 12(11), pp. 1039–1046. 10.1038/nmeth.3581.   edoc
Zhang, Y., Vastenhouw, N. L., Feng, J., Fu, K., Wang, C., Ge, Y., Pauli, A., van Hummelen, P., Schier, A. F. and Liu, X. S. (2014) ‘Canonical nucleosome organization at promoters forms during genome activation’, Genome Research, 24(2), pp. 260–266. 10.1101/gr.157750.113.   edoc | Open Access
Woods, I. G., Schoppik, D., Shi, V. J., Zimmerman, S., Coleman, H. A., Greenwood, J., Soucy, E. R. and Schier, A. F. (2014) ‘Neuropeptidergic signaling partitions arousal behaviors in zebrafish’, Journal of Neuroscience, 34(9), pp. 3142–3160. 10.1523/JNEUROSCI.3529-13.2014.   edoc
Pauli, A., Norris, M. L., Valen, E., Chew, G.-L., Gagnon, J. A., Zimmerman, S., Mitchell, A., Ma, J., Dubrulle, J., Reyon, D., Tsai, S. Q., Joung, J. K., Saghatelian, A. and Schier, A. F. (2014) ‘Toddler: an embryonic signal that promotes cell movement via Apelin receptors’, Science, 343(6172), p. 1248636. 10.1126/science.1248636.   edoc
Richter, C., Woods, I. G. and Schier, A. F. (2014) ‘Neuropeptidergic control of sleep and wakefulness’, Annual Review of Neuroscience, 37, pp. 503–531. 10.1146/annurev-neuro-062111-150447.   edoc
Gagnon, J. A., Valen, E., Thyme, S. B., Huang, P., Akhmetova, L., Pauli, A., Montague, T. G., Zimmerman, S., Richter, C. and Schier, A. F. (2014) ‘Efficient mutagenesis by Cas9 protein-mediated oligonucleotide insertion and large-scale assessment of single-guide RNAs’, PLoS ONE, 9(5), p. e98186. 10.1371/journal.pone.0098186.   edoc | Open Access
Rabani, M., Raychowdhury, R., Jovanovic, M., Rooney, M., Stumpo, D. J., Pauli, A., Hacohen, N., Schier, A. F., Blackshear, P. J., Friedman, N., Amit, I. and Regev, A. (2014) ‘High-resolution sequencing and modeling identifies distinct dynamic RNA regulatory strategies’, Cell, 159(7), pp. 1698–1710. 10.1016/j.cell.2014.11.015.   edoc | Open Access
Schier, A. F. (2014) ‘Obituary: Walter J. Gehring (1939-2014)’, Development, 141(17), pp. 3289–3291. 10.1242/dev.115402.   edoc
Varshney, G. K., Lu, J., Gildea, D. E., Huang, H., Pei, W., Yang, Z., Huang, S. C., Schoenfeld, D., Pho, N. H., Casero, D., Hirase, T., Mosbrook-Davis, D., Zhang, S., Jao, L.-E., Zhang, B., Woods, I. G., Zimmerman, S., Schier, A. F., Wolfsberg, T. G., Pellegrini, M., Burgess, S. M. and Lin, S. (2013) ‘A large-scale zebrafish gene knockout resource for the genome-wide study of gene function’, Genome Research, 23(4), pp. 727–735. 10.1101/gr.151464.112.   edoc
Levitz, J., Pantoja, C., Gaub, B., Janovjak, H., Reiner, A., Hoagland, A., Schoppik, D., Kane, B., Stawski, P., Schier, A. F., Trauner, D. and Isacoff, E. Y. (2013) ‘Optical control of metabotropic glutamate receptors’, Nature neuroscience, 16(4), pp. 507–516. 10.1038/nn.3346.   edoc
Müller, P., Rogers, K. W., Yu, S. R., Brand, M. and Schier, A. F. (2013) ‘Morphogen transport’, Development (Cambridge, England), 140(8), pp. 1621–1638. 10.1242/dev.083519.   edoc
Schier, A. F. (2013) ‘Genomics: Zebrafish earns its stripes’, Nature, 496(7446), pp. 443–444. 10.1038/nature12094.   edoc
Xiong, F., Tentner, A. R., Huang, P., Gelas, A., Mosaliganti, K. R., Souhait, L., Rannou, N., Swinburne, I. A., Obholzer, N. D., Cowgill, P. D., Schier, A. F. and Megason, S. G. (2013) ‘Specified neural progenitors sort to form sharp domains after noisy Shh signaling’, Cell, 153(3), pp. 550–561. 10.1016/j.cell.2013.03.023.   edoc
Chew, G.-L., Pauli, A., Rinn, J. L., Regev, A., Schier, A. F. and Valen, E. (2013) ‘Ribosome profiling reveals resemblance between long non-coding RNAs and 5’ leaders of coding RNAs’, Development, 140(13), pp. 2828–2834. 10.1242/dev.098343.   edoc
Pan, Y. A., Freundlich, T., Weissman, T. A., Schoppik, D., Wang, X. C., Zimmerman, S., Ciruna, B., Sanes, J. R., Lichtman, J. W. and Schier, A. F. (2013) ‘Zebrabow: multispectral cell labeling for cell tracing and lineage analysis in zebrafish’, Development, 140(13), pp. 2835–2846. 10.1242/dev.094631.   edoc | Open Access
Rihel, J. and Schier, A. F. (2013) ‘Sites of action of sleep and wake drugs: insights from model organisms’, Current Opinion in Neurobiology, 23(5), pp. 831–840. 10.1016/j.conb.2013.04.010.   edoc
Schier, A. F. (2013) ‘Should I stay or should I go: neuromodulators of behavioral states’, Cell, 154(5), pp. 955–956. 10.1016/j.cell.2013.08.017.   edoc
Rihel, J. and Schier, A. F. (2012) ‘Behavioral screening for neuroactive drugs in zebrafish’, Developmental Neurobiology, 72(3), pp. 373–385. 10.1002/dneu.20910.   edoc
Pan, Y. A., Choy, M., Prober, D. A. and Schier, A. F. (2012) ‘Robo2 determines subtype-specific axonal projections of trigeminal sensory neurons’, Development, 139(3), pp. 591–600. 10.1242/dev.076588.   edoc
Pan, Y. A., Caron, S. J. C. and Schier, A. F. (2012) ‘BAPTI and BAPTISM birthdating of neurons in zebrafish’, Cold Spring Harbor Protocols, 2012(1), pp. 87–92. 10.1101/pdb.prot067520.   edoc
Stooke-Vaughan, G. A., Huang, P., Hammond, K. L., Schier, A. F. and Whitfield, T. T. (2012) ‘The role of hair cells, cilia and ciliary motility in otolith formation in the zebrafish otic vesicle’, Development, 139(10), pp. 1777–1787. 10.1242/dev.079947.   edoc
Pauli, A., Valen, E., Lin, M. F., Garber, M., Vastenhouw, N. L., Levin, J. Z., Fan, L., Sandelin, A., Rinn, J. L., Regev, A. and Schier, A. F. (2012) ‘Systematic identification of long noncoding RNAs expressed during zebrafish embryogenesis’, Genome research, 22(3), pp. 577–591. 10.1101/gr.133009.111.   edoc
Panizzi, J. R., Becker-Heck, A., Castleman, V. H., Al-Mutairi, D. A., Liu, Y., Loges, N. T., Pathak, N., Austin-Tse, C., Sheridan, E., Schmidts, M., Olbrich, H., Werner, C., Häffner, K., Hellman, N., Chodhari, R., Gupta, A., Kramer-Zucker, A., Olale, F., Burdine, R. D., Schier, A. F., O’Callaghan, C., Chung, E. M. K., Reinhardt, R., Mitchison, H. M., King, S. M., Omran, H. and Drummond, I. A. (2012) ‘CCDC103 mutations cause primary ciliary dyskinesia by disrupting assembly of ciliary dynein arms’, Nature Genetics, 44(6), pp. 714–719. 10.1038/ng.2277.   edoc
Ahrens, M. B., Li, J. M., Orger, M. B., Robson, D. N., Schier, A. F., Engert, F. and Portugues, R. (2012) ‘Brain-wide neuronal dynamics during motor adaptation in zebrafish’, Nature, 485(7399), pp. 471–477. 10.1038/nature11057.   edoc
Huang, P., Xiong, F., Megason, S. G. and Schier, A. F. (2012) ‘Attenuation of Notch and Hedgehog signaling is required for fate specification in the spinal cord’, PLoS Genetics, 8(6), p. e1002762. 10.1371/journal.pgen.1002762.   edoc
Bianco, I. H., Ma, L.-H., Schoppik, D., Robson, D. N., Orger, M. B., Beck, J. C., Li, J. M., Schier, A. F., Engert, F. and Baker, R. (2012) ‘The tangential nucleus controls a gravito-inertial vestibulo-ocular reflex’, Current Biology, 22(14), pp. 1285–1295. 10.1016/j.cub.2012.05.026.   edoc
Low, S. E., Woods, I. G., Lachance, M., Ryan, J., Schier, A. F. and Saint-Amant, L. (2012) ‘Touch responsiveness in zebrafish requires voltage-gated calcium channel 2.1b’, Journal of Neurophysiology, 108(1), pp. 148–159. 10.1152/jn.00839.2011.   edoc | Open Access
Müller, P., Rogers, K. W., Jordan, B. M., Lee, J. S., Robson, D., Ramanathan, S. and Schier, A. F. (2012) ‘Differential diffusivity of Nodal and Lefty underlies a reaction-diffusion patterning system’, Science, 336(6082), pp. 721–724. 10.1126/science.1221920.   edoc | Open Access
Vastenhouw, N. L. and Schier, A. F. (2012) ‘Bivalent histone modifications in early embryogenesis’, Current Opinion in Cell Biology, 24(3), pp. 374–386. 10.1016/j.ceb.2012.03.009.   edoc | Open Access
Xu, C., Fan, Z. P., Müller, P., Fogley, R., DiBiase, A., Trompouki, E., Unternaehrer, J., Xiong, F., Torregroza, I., Evans, T., Megason, S. G., Daley, G. Q., Schier, A. F., Young, R. A. and Zon, L. I. (2012) ‘Nanog-like regulates endoderm formation through the Mxtx2-Nodal pathway’, Developmental Cell, 22(3), pp. 625–638. 10.1016/j.devcel.2012.01.003.   edoc | Open Access
Laukens, B., Jennewein, C., Schenk, B., Vanlangenakker, N., Schier, A., Cristofanon, S., Zobel, K., Deshayes, K., Vucic, D., Jeremias, I., Bertrand, M. J. M., Vandenabeele, P. and Fulda, S. (2011) ‘Smac mimetic bypasses apoptosis resistance in FADD- or caspase-8-deficient cells by priming for tumor necrosis factor α-induced necroptosis’, Neoplasia, 13(10), pp. 971–979. 10.1593/neo.11610.   edoc
Rogers, K. W. and Schier, A. F. (2011) ‘Morphogen gradients: from generation to interpretation’, Annual Review of Cell and Developmental Biology, 27, pp. 377–407. 10.1146/annurev-cellbio-092910-154148.   edoc
Pan, Y. A., Livet, J., Sanes, J. R., Lichtman, J. W. and Schier, A. F. (2011) ‘Multicolor Brainbow imaging in zebrafish’, Cold Spring Harbor Protocols, 2011(1), p. db.prot5546. 10.1101/pdb.prot5546.   edoc
Müller, P. and Schier, A. F. (2011) ‘Extracellular movement of signaling molecules’, Developmental Cell, 21(1), pp. 145–158. 10.1016/j.devcel.2011.06.001.   edoc
Pauli, A., Rinn, J. L. and Schier, A. F. (2011) ‘Non-coding RNAs as regulators of embryogenesis’, Nature reviews. Genetics, 12(2), pp. 136–149. 10.1038/nrg2904.   edoc
Rihel, J., Prober, D. A., Arvanites, A., Lam, K., Zimmerman, S., Jang, S., Haggarty, S. J., Kokel, D., Rubin, L. L., Peterson, R. T. and Schier, A. F. (2010) ‘Zebrafish behavioral profiling links drugs to biological targets and rest/wake regulation’, Science, 327(5963), pp. 348–351. 10.1126/science.1183090.   edoc
Naumann, E. A., Kampff, A. R., Prober, D. A., Schier, A. F. and Engert, F. (2010) ‘Monitoring neural activity with bioluminescence during natural behavior’, Nature Neuroscience, 13(4), pp. 513–520. 10.1038/nn.2518.   edoc
Vastenhouw, N. L., Zhang, Y., Woods, I. G., Imam, F., Regev, A., Liu, X. S., Rinn, J. and Schier, A. F. (2010) ‘Chromatin signature of embryonic pluripotency is established during genome activation’, Nature, 464(7290), pp. 922–926. 10.1038/nature08866.   edoc
Harvey, S. A., Tümpel, S., Dubrulle, J., Schier, A. F. and Smith, J. C. (2010) ‘no tail integrates two modes of mesoderm induction’, Development, 137(7), pp. 1127–1135. 10.1242/dev.046318.   edoc
Rihel, J., Prober, D. A. and Schier, A. F. (2010) ‘Monitoring sleep and arousal in zebrafish’, Methods in cell biology, 100, pp. 281–294. 10.1016/B978-0-12-384892-5.00011-6.   edoc
Huang, P. and Schier, A. F. (2009) ‘Dampened Hedgehog signaling but normal Wnt signaling in zebrafish without cilia’, Development, 136(18), pp. 3089–3098. 10.1242/dev.041343.   edoc
Schier, A. F. and Needleman, D. (2009) ‘Developmental biology: Rise of the source-sink model’, Nature, 461(7263), pp. 480–481. 10.1038/461480a.   edoc
Schier, A. F. (2009) ‘Nodal morphogens’, Cold Spring Harbor Perspectives in Biology, 1(5), p. a003459. 10.1101/cshperspect.a003459.   edoc
Choi, P. S., Zakhary, L., Choi, W.-Y., Caron, S., Alvarez-Saavedra, E., Miska, E. A., McManus, M., Harfe, B., Giraldez, A. J., Horvitz, H. R., Schier, A. F. and Dulac, C. (2008) ‘Members of the miRNA-200 family regulate olfactory neurogenesis’, Neuron, 57(1), pp. 41–55. 10.1016/j.neuron.2007.11.018.   edoc
Prober, D. A., Zimmerman, S., Myers, B. R., McDermott, B. M., Kim, S.-H., Caron, S., Rihel, J., Solnica-Krezel, L., Julius, D., Hudspeth, A. J. and Schier, A. F. (2008) ‘Zebrafish TRPA1 channels are required for chemosensation but not for thermosensation or mechanosensory hair cell function’, Journal of Neuroscience, 28(40), pp. 10102–10110. 10.1523/JNEUROSCI.2740-08.2008.   edoc
de Campos-Baptista, M. I. M., Holtzman, N. G., Yelon, D. and Schier, A. F. (2008) ‘Nodal signaling promotes the speed and directional movement of cardiomyocytes in zebrafish’, Developmental Dynamics, 237(12), pp. 3624–3633. 10.1002/dvdy.21777.   edoc
Knaut, H. and Schier, A. F. (2008) ‘Clearing the path for germ cells’, Cell, 132(3), pp. 337–339. 10.1016/j.cell.2008.01.023.   edoc
Woods, I. G. and Schier, A. F. (2008) ‘Targeted mutagenesis in zebrafish’, Nature Biotechnology, 26(6), pp. 650–651. 10.1038/nbt0608-650.   edoc | Open Access
Douglass, A. D., Kraves, S., Deisseroth, K., Schier, A. F. and Engert, F. (2008) ‘Escape behavior elicited by single, channelrhodopsin-2-evoked spikes in zebrafish somatosensory neurons’, Current Biology, 18(15), pp. 1133–1137. 10.1016/j.cub.2008.06.077.   edoc | Open Access
Caron, S. J. C., Prober, D., Choy, M. and Schier, A. F. (2008) ‘In vivo birthdating by BAPTISM reveals that trigeminal sensory neuron diversity depends on early neurogenesis’, Development, 135(19), pp. 3259–3269. 10.1242/dev.023200.   edoc | Open Access
Choi, W.-Y., Giraldez, A. J. and Schier, A. F. (2007) ‘Target protectors reveal dampening and balancing of Nodal agonist and antagonist by miR-430’, Science, 318(5848), pp. 271–274. 10.1126/science.1147535.   edoc
Bennett, J. T., Joubin, K., Cheng, S., Aanstad, P., Herwig, R., Clark, M., Lehrach, H. and Schier, A. F. (2007) ‘Nodal signaling activates differentiation genes during zebrafish gastrulation’, Developmental Biology, 304(2), pp. 525–540. 10.1016/j.ydbio.2007.01.012.   edoc | Open Access
Schier, A. F. (2007) ‘The maternal-zygotic transition: death and birth of RNAs’, Science, 316(5823), pp. 406–407. 10.1126/science.1140693.   edoc
Bennett, J. T., Stickney, H. L., Choi, W.-Y., Ciruna, B., Talbot, W. S. and Schier, A. F. (2007) ‘Maternal nodal and zebrafish embryogenesis’, Nature, 450(7167), pp. E1–2; discussion E2. 10.1038/nature06314.   edoc
Karkera, J. D., Lee, J. S., Roessler, E., Banerjee-Basu, S., Ouspenskaia, M. V., Mez, J., Goldmuntz, E., Bowers, P., Towbin, J., Belmont, J. W., Baxevanis, A. D., Schier, A. F. and Muenke, M. (2007) ‘Loss-of-function mutations in growth differentiation factor-1 (GDF1) are associated with congenital heart defects in humans’, American Journal of Human Genetics, 81(5), pp. 987–994. 10.1086/522890.   edoc | Open Access
Prober, D. A., Rihel, J., Onah, A. A., Sung, R.-J. and Schier, A. F. (2006) ‘Hypocretin/orexin overexpression induces an insomnia-like phenotype in zebrafish’, Journal of Neuroscience, 26(51), pp. 13400–13410. 10.1523/JNEUROSCI.4332-06.2006.   edoc | Open Access
Mishima, Y., Giraldez, A. J., Takeda, Y., Fujiwara, T., Sakamoto, H., Schier, A. F. and Inoue, K. (2006) ‘Differential regulation of germline mRNAs in soma and germ cells by zebrafish miR-430’, Current Biology, 16(21), pp. 2135–2142. 10.1016/j.cub.2006.08.086.   edoc | Open Access
Obara, T., Mangos, S., Liu, Y., Zhao, J., Wiessner, S., Kramer-Zucker, A. G., Olale, F., Schier, A. F. and Drummond, I. A. (2006) ‘Polycystin-2 immunolocalization and function in zebrafish’, Journal of the American Society of Nephrology, 17(10), pp. 2706–2718. 10.1681/ASN.2006040412.   edoc | Open Access
Ciruna, B., Jenny, A., Lee, D., Mlodzik, M. and Schier, A. F. (2006) ‘Planar cell polarity signalling couples cell division and morphogenesis during neurulation’, Nature, 439(7073), pp. 220–224. 10.1038/nature04375.   edoc | Open Access
Giraldez, A. J., Mishima, Y., Rihel, J., Grocock, R. J., Van Dongen, S., Inoue, K., Enright, A. J. and Schier, A. F. (2006) ‘Zebrafish MiR-430 promotes deadenylation and clearance of maternal mRNAs’, Science, 312(5770), pp. 75–79. 10.1126/science.1122689.   edoc
Schier, A. F. and Giraldez, A. J. (2006) ‘MicroRNA function and mechanism: insights from zebra fish’, Cold Spring Harbor Symposia on Quantitative Biology, 71, pp. 195–203. 10.1101/sqb.2006.71.055.   edoc
Schier, A. F. (2005) ‘Axis formation: squint comes into focus’, Current Biology, 15(24), pp. R1002-R1005. 10.1016/j.cub.2005.11.051.   edoc
Schier, A. F. and Talbot, W. S. (2005) ‘Molecular genetics of axis formation in zebrafish’, Annual Review of Genetics, 39, pp. 561–613. 10.1146/annurev.genet.37.110801.143752.   edoc
Sagasti, A., Guido, M. R., Raible, D. W. and Schier, A. F. (2005) ‘Repulsive interactions shape the morphologies and functional arrangement of zebrafish peripheral sensory arbors’, Current Biology, 15(9), pp. 804–814. 10.1016/j.cub.2005.03.048.   edoc
Le Good, J. A., Joubin, K., Giraldez, A. J., Ben-Haim, N., Beck, S., Chen, Y., Schier, A. F. and Constam, D. B. (2005) ‘Nodal stability determines signaling range’, Current Biology, 15(1), pp. 31–36. 10.1016/j.cub.2004.12.062.   edoc
Tyurina, O. V., Guner, B., Popova, E., Feng, J., Schier, A. F., Kohtz, J. D. and Karlstrom, R. O. (2005) ‘Zebrafish Gli3 functions as both an activator and a repressor in Hedgehog signaling’, Developmental Biology, 277(2), pp. 537–556. 10.1016/j.ydbio.2004.10.003.   edoc
Dutta, S., Dietrich, J.-E., Aspöck, G., Burdine, R. D., Schier, A., Westerfield, M. and Varga, Z. M. (2005) ‘pitx3 defines an equivalence domain for lens and anterior pituitary placode’, Development, 132(7), pp. 1579–1590. 10.1242/dev.01723.   edoc
Kramer-Zucker, A. G., Olale, F., Haycraft, C. J., Yoder, B. K., Schier, A. F. and Drummond, I. A. (2005) ‘Cilia-driven fluid flow in the zebrafish pronephros, brain and Kupffer’s vesicle is required for normal organogenesis’, Development, 132(8), pp. 1907–1921. 10.1242/dev.01772.   edoc
Giraldez, A. J., Cinalli, R. M., Glasner, M. E., Enright, A. J., Thomson, J. M., Baskerville, S., Hammond, S. M., Bartel, D. P. and Schier, A. F. (2005) ‘MicroRNAs regulate brain morphogenesis in zebrafish’, Science, 308(5723), pp. 833–838. 10.1126/science.1109020.   edoc
Knaut, H., Blader, P., Strähle, U. and Schier, A. F. (2005) ‘Assembly of trigeminal sensory ganglia by chemokine signaling’, Neuron, 47(5), pp. 653–666. 10.1016/j.neuron.2005.07.014.   edoc
Schier, A. F. (2004) ‘Developmental biology: tail of decay’, Nature, 427(6973), pp. 403–404. 10.1038/427403a.   edoc
Schier, A. (2004) ‘Alexander Schier’, Current Biology, 14(13), p. R494. 10.1016/j.cub.2004.06.032.   edoc
Cheng, S. K., Olale, F., Brivanlou, A. H. and Schier, A. F. (2004) ‘Lefty blocks a subset of TGFbeta signals by antagonizing EGF-CFC coreceptors’, PLoS biology, 2(2), p. E30. 10.1371/journal.pbio.0020030.   edoc | Open Access
Karlstrom, R. O., Tyurina, O. V., Kawakami, A., Nishioka, N., Talbot, W. S., Sasaki, H. and Schier, A. F. (2003) ‘Genetic analysis of zebrafish gli1 and gli2 reveals divergent requirements for gli genes in vertebrate development’, Development, 130(8), pp. 1549–1564. 10.1242/dev.00364.   edoc
Schier, A. F. (2003) ‘Chemokine signaling: rules of attraction’, Current Biology, 13(5), pp. R192-R194. 10.1016/s0960-9822(03)00122-2.   edoc
Kunwar, P. S., Zimmerman, S., Bennett, J. T., Chen, Y., Whitman, M. and Schier, A. F. (2003) ‘Mixer/Bon and FoxH1/Sur have overlapping and divergent roles in Nodal signaling and mesendoderm induction’, Development, 130(23), pp. 5589–5599. 10.1242/dev.00803.   edoc
Dougan, S. T., Warga, R. M., Kane, D. A., Schier, A. F. and Talbot, W. S. (2003) ‘The role of the zebrafish nodal-related genes squint and cyclops in patterning of mesendoderm’, Development, 130(9), pp. 1837–1851. 10.1242/dev.00400.   edoc
Schier, A. F. (2003) ‘Nodal signaling in vertebrate development’, Annual review of cell and developmental biology, 19, pp. 589–621. 10.1146/annurev.cellbio.19.041603.094522.   edoc
Cheng, S. K., Olale, F., Bennett, J. T., Brivanlou, A. H. and Schier, A. F. (2003) ‘EGF-CFC proteins are essential coreceptors for the TGF-beta signals Vg1 and GDF1’, Genes and Development, 17(1), pp. 31–36. 10.1101/gad.1041203.   edoc | Open Access
Kimelman, D. and Schier , A. F. (2002) ‘Mesoderm Induction and Patterning’, in Solnica-Krezel, L. (ed.) Pattern Formation in Zebrafish. Heidelberg: Springer (Results and Problems in Cell Differentiation), pp. 15–27. 10.1007/978-3-540-46041-1_2.   edoc
Ciruna, B., Weidinger, G., Knaut, H., Thisse, B., Thisse, C., Raz, E. and Schier, A. F. (2002) ‘Production of maternal-zygotic mutant zebrafish by germ-line replacement’, Proceedings of the National Academy of Sciences of the United States of America, 99(23), pp. 14919–14924. 10.1073/pnas.222459999.   edoc | Open Access
Moon, H.-S., Jacobson, E. M., Khersonsky, S. M., Luzung, M. R., Walsh, D. P., Xiong, W., Lee, J. W., Parikh, P. B., Lam, J. C., Kang, T.-W., Rosania, G. R., Schier, A. F. and Chang, Y.-T. (2002) ‘A novel microtubule destabilizing entity from orthogonal synthesis of triazine library and zebrafish embryo screening’, Journal of the American Chemical Society, 124(39), pp. 11608–11609. 10.1021/ja026720i.   edoc
Chen, Y. and Schier, A. F. (2002) ‘Lefty proteins are long-range inhibitors of squint-mediated nodal signaling’, Current Biology, 12(24), pp. 2124–2128. 10.1016/s0960-9822(02)01362-3.   edoc
de la Cruz, J. M., Bamford, R. N., Burdine, R. D., Roessler, E., Barkovich, J. A., Donnai, D., Schier, A. F. and Muenke, M. (2002) ‘A loss-of-function mutation in the CFC domain of TDGF1 is associated with human forebrain defects’, Human genetics, 110(5), pp. 422–428. 10.1007/s00439-002-0709-3.   edoc
Yamashita, S., Miyagi, C., Carmany-Rampey, A., Shimizu, T., Fujii, R., Schier, A. F. and Hirano, T. (2002) ‘Stat3 Controls Cell Movements during Zebrafish Gastrulation’, Developmental Cell, 2(3), pp. 363–375. 10.1016/s1534-5807(02)00126-0.   edoc