Vertebrate Development and Behavior → Schierlab Although scientific knowledge has advanced enormously in the last thirty years, we still only superficially understand how a single fertilized egg cell develops to form a…

IMCF guidelines 1. General booking Rules: The user can book a microscope only after having received the appropriate introduction. The instruments can be booked up to 14 days in advance. During daily working hours (9-17h),…

Available Microscope Systems Searching for a decision tree? Clicking on the image below and you will be directed to our internal documentation that will help you to decide which system is best for your research project. If…

Thin Sectioning Application To determine the ultrastructure of whole tissues and cells at ~2nm resolution by transmission electron microscopy (TEM). Method Tissues or cells are chemically fixed, dehydrated, embedded in resin…

Structure, function, and evolution of genome-wide regulatory networks Most projects that we pursue concern the functioning and evolution of genome-wide regulatory systems in organisms ranging from bacteria to humans. The…

Cell receptor dynamics and signaling G protein-coupled receptors (GPCRs) are a large family of membrane proteins crucial for cell signaling and the target of about 35 percent of all drugs. Despite that the knowledge of GPCRs…

Chromosomes in 3D The developmentally dynamic nucleus How are chromosomes organized within nuclei? And how does organization impact developmental events? The nucleus is very dynamic during embryogenesis, in part because…

How the brain controls sleep Sleep is essential, yet its function remains one of biology’s biggest mysteries. A short or poor night of sleep is usually followed by longer and/or deeper periods of sleep. The existence of such…

Computational structure biology Protein structure modeling The main interest of our group is the development of methods and algorithms for molecular modeling and simulations of three-dimensional protein structures and their…

Image Gallery To share your scientific images taken at the IMCF in this gallery, please send your images to Alexia with a short description. The images contained within this gallery remain the copyright of the Biozentrum.…