TOR signaling and control of cell growth Fig. 1: Architecture of human mTOR complex 1 Introduction Cell growth is highly regulated. Cells respond to nutrients or other appropriate growth stimuli by up-regulating…
In certain infectious diseases, antibiotics are less effective than expected, as seen in infections caused by Salmonella bacteria, which can lead to illnesses such as typhoid fever. For many years, researchers believed that…
How cells defend their cytosol against bacteria: LPS ubiquitylation and other tricks Intracellular pathogens colonize specific subcellular niches, reflecting the pathogen's need for host factors and nutrients as well as its…
For about one hundred years it has been known that nutrient restriction and moderate stress can significantly prolong life. The researchers led by Prof. Mihaela Zavolan and Prof. Anne Spang, both at the Biozentrum of the…
In recent years, the growing threat of antimicrobial resistance has become widely recognized. However, much less is known about drug-tolerant pathogens, which also complicate the treatment of bacterial infections. These…
Synopsis Antibiotic resistance has re-emerged as a critical problem of contemporary medicine. I will discuss the biological processes contributing to the spread of antibiotic resistance. In this talk, I will ask how…
Einblicke Biozentrum Public lecture series: «Einblicke Biozentrum» Scientists from the Biozentrum invite all interested persons to learn about their latest research. The lecture series takes the visitors on a journey into…
If a cell encounters a stress situation, whether it is due to nutrient restriction or osmotic shock, the cell reacts immediately to ensure its survival. Prof. Anne Spang’s research group at the Biozentrum of the University…
From Ion to Insight: How Magnesium Could Change the Way We See Liver Disease Magnesium is one of the most abundant intracellular cations, yet its role in liver biology has remained largely overlooked. Traditionally viewed as…
People are living longer than ever, but a long life doesn’t necessarily mean a healthy one. For many, the question isn’t so much “How old do I want to get?” but rather “How do I want to get old.” While lifespan refers to the…
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