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Markus Affolter

Prof. Markus Affolter about CRISPR/Cas9 Only a few years ago, the gene scissors CRISPR/Cas9 were discovered. It has revolutionized the scientific world, as it has never been so easy to change the genome of organisms. CRISPR…


Numerous genes important for muscle-nerve connection identified

Walking, breathing, or writing – these movements would not be possible without our muscles. The instructions are given by the nerves that communicate with the muscles through neuromuscular junctions. Damage to or loss of…


Survival trick: Pathogen taps iron source in immune cells

Our body keeps bacterial pathogens under control by restricting their access to essential nutrients such as iron. Iron is crucial for all living organisms. When bacteria are deprived of iron, they stop growing and…


GPS for proteins: Tracking the motions of cell receptors

G protein-coupled receptors are embedded in the cell membrane and transmit signals from the outside to the inside of the cell. Because of their vast diversity and crucial role in the body, GPCRs are targeted by many drugs,…


PhD Fellowships

Biozentrum PhD Fellowships Program Share your passion for life sciences. If you are talented and highly motivated, want to broaden your horizons and are interested in a wide range of research topics, apply for one of the…


Björn Grünenfelder

From block course to cooking class. July 2018 In the block course they were simply known as the Nirvanas. Twenty years on, in a cooking class, their hair now short, yet each slipped back into his old role. The Biozentrum…


Anna Mandinova

Well prepared for life July 2018 What a coincidence. Shortly, after we sent out our request for an interview, Harvard Professor Anna Mandinova replied that she is currently traveling through Europe and Switzerland.…


Everything in balance? How a molecular switch controls lipid metabolism

All organisms need energy to live. We get energy from various components of our food. Our body uses a part of this energy directly and stores the rest. While glucose serves as an immediately available energy source, fats are…


Autism: How gene alteration modifies social behavior

Autism occurs in about one percent of the population and is characterized by alterations in communication, repetitive behavior and social difficulties. There are numerous genetic factors involved in the development of…


Therapy for muscular dystrophy: A new start-up at the Biozentrum

Congenital muscular dystrophy is a rare hereditary disease which cannot be cured. The more than 30 known forms of this neuromuscular disease differ in the type of genetic defect and in the severity of disease progression.…