In Switzerland, about 650 new cases of liver cancer are diagnosed every year. The incidence of the malignant and aggressive liver cell carcinoma has doubled in the last 20 years, especially in developed countries. One…

The Biozentrum start-up Aukera Therapeutics was selected to join the BaseLaunch Accelerator Program. With its qualification for this program, the biotech venture receives funding of up to 500,000 Swiss francs as well as…

Muscle aging Rapid advances in treating life-threatening, age-related diseases, such as cancer and cardiovascular disease, have extended human lifespan in many developed countries. However, greater longevity has meant more…

The project entitled «Development of a lead compound for specific mTORC1 inhibition» is the first Innosuisse funded project at the Biozentrum. Replacing the former Swiss Commission for Technology and Innovation (CTI), the…

Principles of intracellular organization Correct intracellular localization of proteins and mRNA ensures cell survival. Specific localization of these molecules allows the development of multicellular organisms such as…

Already in our best years, our muscles begin to shrink and their strength dwindles. Unfortunately, this is a natural part of aging. For some people, the decline in muscle mass and function is excessive. This condition,…

Proteins perform various jobs in cells, they catalyze thousands of biochemical reactions, relay signals and are required for building cellular structures and transport processes. Within every single cell of our body vast…

G3: Frontiers in RNA Biology – 13186 (2 hrs/week; 2 CP; Fall 2025) M. Bühler , H. Grosshans The discovery that RNA is not only a carrier of genetic information or a structural scaffold in ribonucleoprotein particles but can…

Publication list - curated & annotated Recent highlights Bacteria use a general danger signal to trigger biofilm formation - Nature Microbiology 2025 Mechanical properties of biofilms measured with spatial resolution -…

TOR signaling and control of cell growth Fig. 1: Architecture of human mTOR complex 1 Introduction Cell growth is highly regulated. Cells respond to nutrients or other appropriate growth stimuli by up-regulating…