Bacterial effectors and their many ways to modulate immune signaling Many Gram-negative bacteria modulate host immune responses through the activity of effector proteins delivered by secretion systems. The downstream changes…
Conformational ensembles of the human intrinsically disordered proteome Intrinsically disordered proteins and regions (collectively IDRs) are pervasive across proteomes in all kingdoms of life, help shape biological…
Conformational ensembles of the human intrinsically disordered proteome Intrinsically disordered proteins and regions (collectively IDRs) are pervasive across proteomes in all kingdoms of life, help shape biological…
Of predators, vampires, and ghosts: shedding light on the lifecycles of Bdellovibriobacteria Bdellovibrio bacteriovorus is an obligate predatory bacterium that exclusively feeds upon other bacteria after invading their…
A philosophical perspective on science January 2023 “The stereotype of a thinker sitting in a room all alone with their brilliant ideas has never been true.” Biozentrum alumnus Marcel Weber must know. He is Professor of…
Interview with Karolin Berneiser Inspired by a colleague’s experience, Karolin Berneiser applied for the Biozentrum PhD Fellowships program. She is not only enthusiastic about the interdisciplinary and international research…
Assault, Siege, Trojan Horses or Gentle Disarmament: Molecular Strategies to Fight Bacterial Infections Multidrug resistant bacterial pathogens have become a major health concern. We have investigated various chemical…
Eco-evolutionary dynamics of phage-bacteria interactions Microbial communities in all environments are shaped by viral predators. Yet, resolving which viruses (phages) and bacteria are interacting, and how strongly viruses…
Adjusting organ size during development The sizes of living organisms span over twenty orders of magnitude or so. Mechanistically, the control of organ and organismal size results from the complex integration of autonomous…
How cells defend their cytosol against bacteria: LPS ubiquitylation and other tricks Intracellular pathogens colonize specific subcellular niches, reflecting the pathogen's need for host factors and nutrients as well as its…
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