When our innate immune system detects a pathogen it mounts a potent inflammatory response that has the capacity to contain and eliminate the infection, but typically also causes significant damage to the inflamed tissue.…
From tackling nosocomial pathogens to decoding memory storage, Biozentrum scientists made significant advances in the past year. Prof. Urs Jenal’s team, for example, revealed how Pseudomonas aeruginosa exploits goblet cells…
Cells live and survive by taking up proteins, recycling and reusing or degrading them. The proteins are located on the cell surface and are transported from here into the cell’s interior. About 80 percent of these membrane…
With the revolutionary CRISPR/Cas technology, the DNA of living organisms can be precisely altered. Using a guide RNA that recognizes a specific DNA sequence, Cas9 protein is recruited to that sequence and cuts the DNA. This…
Genetic information is protected in the cell nucleus by a membrane that contains numerous nuclear pores. These pores facilitate the traffic of proteins known as importins that deliver molecular cargoes between the nucleus…
Lucia Du, Postdoc, Group Schier Can you provide us some insights into your research? Development is a remarkably robust process that results in the generation of organs with reproducible size, shape and functions. My…
Testimonial of Míriam Condeminas Rodríguez University of Barcelona, Spain, Research Group Torsten Schwede Where do you come from and what do you study? I come from Barcelona in Spain. I am studying chemistry and have just…
The inside of a cell provides as a hiding place for various pathogens. By residing in the cell, the bacteria can evade the immune response and spread within the body. Among these invaders are Burkholderia bacteria, including…
Prof. Richard Neher talks about influenza Every year we are plagued by a new flu epidemic. Richard Neher and his team are investigating the spread and evolution of the flu virus. They also predict which virus is in the…
When pathogens infect an organism, the defense system immediately starts to fight the bacteria. To escape the patrolling immune cells, some bacteria invade and replicate inside host cells. However, the host has developed…
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