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Organellomics: AI-driven deep organellar phenotyping of human neurons

Organellomics: AI-driven deep organellar phenotyping of human neurons Systematic assessment of organelle architectures in cells, known as the organellome, could provide valuable insights into cellular states and disease…


G5: Translational Control and Post-Translational Protein Modification

G5: Translational Control and Post-Translational Protein Modification – 18367 (2 hrs/week; 2 CP; Fall 2026) J.Chao , M. Hall, A. Schmidt This course will describe the components of the translational apparatus and their…


Cell Analysis Guidelines

Cell Analysis Guidelines General Rules The FACS Core Facility (FCF) Analyzer Room is located in the Biozentrum on the 10th floor in the room 10.044, on Quadrant 2. The laboratory is approved at Biosafety Level 2 (BSL-2).…


Research Group Stephan Grzesiek

Understanding biomolecular function All biological processes, for example cell division, infection or development of cancer, are based on specific interactions between biomolecules. These interactions are consequences of the…


An Innovative Approach to Chronic Kidney Disease Treatment by improving Oxidative Stress and Lipid Imbalance

An Innovative Approach to Chronic Kidney Disease Treatment by improving Oxidative Stress and Lipid Imbalance Currently, chronic kidney disease (CKD) lacks effective therapies, since it intricately encompasses multiple…


School Children

Internships for school children To get a taste for research and have the opportunity to use their own hands, or a pipette as the case may be, and slip into the role of a scientist, is also made possible for school children…


Proteomics Across Deep Evolutionary Time

Proteomics Across Deep Evolutionary Time Nearly half of human genes arose from ancestral versions dating back to the Last Eukaryotic Common Ancestor (LECA) roughly 1.5 billion years ago. Many current genetic diseases and…


I5: Introduction to Protein Interaction Analysis by Affinity Purification – Mass Spectrometry

I5: Introduction to Protein Interaction Analysis by Affinity Purification – Mass Spectrometry – 34604 (3 days; 1 CP; Spring & Fall) Course dates Spring: to be announced Course dates Fall: 04.11. - 06.11.25 Thomas Bock ,…


Purinosome: assembly mechanism and interplay with mitochondria

Purinosome: assembly mechanism and interplay with mitochondria Purinosomes represent biomolecular condensates that compartmentalize enzymes in the de novo purine synthesis (DNPS) pathway to enhance pathway flux. However, the…


J.C.W. Shepherd Prize

J.C.W. Shepherd PhD Student Prize of the Biozentrum, University of Basel Background The wife of John Charles Warren Shepherd, a former collaborator of Walter Gehring (see Shepherd JC et al. 1984 Nature, Shepherd JC et al.…