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Blood vessel formation: how the vascular cells respond to blood pressure

Throughout our body there is a dense, widely ramified network of blood vessels. It is estimated to be about 150,000 kilometers in length. The vessels supply all cells, even those in most far away regions of the body with…


Neutralizing antibodies control bacterial infection

Bartonella are bacteria that are transmitted from blood-sucking insects to mammals, including humans. There they enter the red blood cells and cause various symptoms. An example of such a human infection with a worldwide…


Gene transfer keeps bacteria fit

Bartonella are bacteria that can cause diverse infectious diseases in man, such as cat-scratch disease. In order to prevent the accumulation of mutations during the infection cycle, pathogens require efficient DNA repair…


The mystery of sleep: How does the brain know when it’s time to sleep?

Sleep is universal and essential: not only humans, but even flies and jellyfish sleep for a significant portion of the day. Like eating or mating, sleep is also controlled by motivational drives. Our drive to sleep increases…


Researchers discover “folding factories” for proteins

Proteins are the workhorses of our cells: They transport substances, digest nutrients and serve as building blocks. To perform this wide range of tasks, they must be folded correctly. This process is ensured by an arsenal of…


Study challenges a long-held view in cell biology

Coronins are found throughout the animal kingdom, from single-celled amoebae to humans, and are involved in many vital processes including immunity, development and cell survival. For decades, textbooks and hundreds of…


Sira Borja

Sira Borja - Physics student from Spain Why did you apply for the internship? I wanted to get my first taste of actual research, as I had never done an internship before. In addition, when I discovered the different research…


New way to improve the efficacy of innovative RNA therapies

In modern medicine, personalized therapies are becoming increasingly important – particularly in the treatment of genetic diseases. One such promising approach is the use of so-called antisense oligonucleotides (ASOs). These…


New insights into blood vessel formation

Blood vessels run throughout the entire body, delivering nutrients and oxygen through the circulating blood. During vessel formation, cells first form local lumens, which then fuse to form a continuous tubular network. The…


Protected while sleeping: How pathogens survive antibiotic treatment

In recent years, the growing threat of antimicrobial resistance has become widely recognized. However, much less is known about drug-tolerant pathogens, which also complicate the treatment of bacterial infections. These…