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Highlights

Biozentrum Highlights Nobel Prize 1978 | Prof. Werner Arber Emeritus page Albert Lasker Basic Medical Research Award 2017 | Prof. Michael N. Hall Research Group Michael Hall Breakthrough Prize in Life Sciences 2014 | Prof.…


Projects

Research projects We investigate the physiology of bacterial pathogens ( Salmonella , Pseudomonas , Staphylococcus ) in infected rodent and human tissues, focusing on single-cell behavior and potential applications for novel…


Movies

Movies Bacterial nanosized speargun Dynamics of T6SS sheath in Vibrio cholerae. (Basler et al., Nature 2012) Dueling between green Pseudomonas aeruginosa cells (ClpV-GFP) and killing of red Vibrio cholerae cells…


"Einblicke Biozentrum" on the novel coronavirus outbreak

At the end of 2019, physicians in Wuhan, China, described a cluster of pneumonia associated with an unknown virus. Only two weeks later scientists had determined that the pathogen is a new type of coronavirus that is related…


Thermo Fisher Scientific Glacios TEM

Thermo Fisher Scientific Glacios TEM Configuration 200kV X-FEG optics. C-TWIN objective lens. Autoloader for multi-grid loading at cryo-LN2 temperature and automated exchange of grid to column. The Glacios instrument is…


Host tissue responses to bacterial infection: A story of Mice and Men

Host tissue responses to bacterial infection: A story of Mice and Men Bacterial infection takes place in the complex microenvironment of the host tissue. Dependent on the infection type, this environment varies dramatically…


Seraphine Lüscher

Interview with Seraphine Lüscher She practically adopted the protein assigned to her in the Experimental Molecular Biology course. Being able to conduct experiments from A to Z already in her second year of studies was a…


NMJ maintenance and remodeling

NMJ maintenance and remodeling The neuromuscular junction (NMJ) is a chemical synapse that transmits motor neuron action potentials into muscle fiber action potentials (see Figure below). Without this connection, muscle…


Comparative genomics at scale in the post-AlphaFold era

Comparative genomics at scale in the post-AlphaFold era Within a decade, various consortia under the Earth BioGenome umbrella aim to sequence 1.5M eukaryotes. All these genomes are connected through life’s common origin, yet…


Molecular Medicine, Physiology, Metabolism and Aging

Molecular Medicine, Physiology, Metabolism and Aging Prof. Dirk Bumann Single-cell pathogen activities during infection and treatment Prof. Christoph Dehio Molecular mechanisms of chronic bacterial infections Prof. Fiona…