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Molecule-Scale Resolution and Dynamics in Fluorescence Microscopy

Molecule-Scale Resolution and Dynamics in Fluorescence Microscopy I will show how an in-depth description of the basic principles of diffraction-unlimited fluorescence microscopy has spawned MINFLUX [1-4], a recent…


Publications, curated

Publication list - curated & annotated Recent highlights Bacteria use a general danger signal to trigger biofilm formation - Nature Microbiology 2025 Mechanical properties of biofilms measured with spatial resolution -…


DNA transfer by conjugation in live-cells

DNA transfer by conjugation in live-cells DNA conjugation is a contact-dependent horizontal gene transfer mechanism responsible for the dissemination of metabolic properties in bacteria, including drug resistance. Despite…


Projects

Research Projects The central theme of our research is to understand how stochastic interactions of cells and molecules control the functional behaviour of multicellular systems. We specifically focus on how cells interact…


Awards

Fellowships and Awards Year Award Recipient(s) 2023 EMBO Membership BASLER Marek 2021 Boehringer Ingelheim Fonds PhD fellowship CHEUNG Hoi Ching 2021 Novartis FreeNovation Grant KOLESNIKOV Maxim, PLUM Miro, BASLER Marek 2020…


PhD Fellows

PhD Fellows 2025 Daniil Bobrovskiy Group Schier A. Group Brückner D. Group Schier A. Group Brückner D. Biozentrum, Room: 11.Q1 daniil.bobrovskii unibas ch Leo Flehinghaus Group Brückner D. Group Brückner D. Biozentrum, Room:…


Projects

Research projects We investigate the physiology of bacterial pathogens ( Salmonella , Pseudomonas , Staphylococcus ) in infected rodent and human tissues, focusing on single-cell behavior and potential applications for novel…


Inspiring Biozentrum Symposium 2020

The Biozentrum organizes a symposium for its employees and students annually. This provides an insight into other areas of research, as well as an overview of the many projects being carried out. Furthermore, the symposium…


Cholesterol disrupts lipid metabolism in the cell

Our cells continuously receive external signals, which are transmitted across the cell membrane into the cell, to be processed in the cell nucleus. Various signaling pathways are found in the cell membrane. One is the…


Laura de Smalen

Laura de Smalen, PhD Student, Group Handschin Why did you decide to do a PhD? During my bachelor's in Nutrition and Dietetics, I developed a strong interest in the causes and mechanisms that underlie the human diseases that…