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DNA transfer by conjugation in live-cells

DNA transfer by conjugation in live-cells DNA conjugation is a contact-dependent horizontal gene transfer mechanism responsible for the dissemination of metabolic properties in bacteria, including drug resistance. Despite…


Molecule-Scale Resolution and Dynamics in Fluorescence Microscopy

Molecule-Scale Resolution and Dynamics in Fluorescence Microscopy I will show how an in-depth description of the basic principles of diffraction-unlimited fluorescence microscopy has spawned MINFLUX [1-4], a recent…


Publications, curated

Publication list - curated & annotated Recent highlights Bacteria use a general danger signal to trigger biofilm formation - Nature Microbiology 2025 Mechanical properties of biofilms measured with spatial resolution -…


Projects

Cell signaling and dynamics in bacterial growth, adaptation, and persistence Our studies aim at understanding the molecular and cellular principles involved in the growth, differentiation and behavior of bacterial cells. We…


Novel strategies for treating bacterial infections without antibiotics

Novel strategies for treating bacterial infections without antibiotics Murphy Lam Yim Wan, Ines Ambite, Thi Hien Tran, Shahram Ahmadi, Atefeh Nazari, Arunima Chaudhuri, Farhan Haq, Christian Krintel, Björn Wullt, Florian…


Spore formation in Clostridioides difficile is governed by small RNAs

Spore formation in Clostridioides difficile is governed by small RNAs Spore formation in Clostridioides difficile is governed by small RNAs - an unexpected twist on the classic model of sporulation initiation. Clostridioides…


PhD Fellows

PhD Fellows 2025 Daniil Bobrovskiy Group Schier A. Group Brückner D. Group Schier A. Group Brückner D. Biozentrum, Room: 11.Q1 daniil.bobrovskii unibas ch Leo Flehinghaus Group Brückner D. Group Brückner D. Biozentrum, Room:…


Projects

Research Projects The central theme of our research is to understand how stochastic interactions of cells and molecules control the functional behaviour of multicellular systems. We specifically focus on how cells interact…


Inner “clockwork” sets the time for cell division in bacteria

The ability of pathogens to multiply in the host is crucial for the spread of infections. The speed of bacterial division greatly depends on the environmental conditions. Under unfavorable conditions, such as nutrient…


Palmer Bassett

Interview with Palmer Bassett She has a passion for the tiny worm C. elegans – not only because it offers so many possibilities for discovery but also because it brings together so many interesting people. This and the fact…