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C3: Molecular Mechanisms of Development –

C3: Molecular Mechanisms of Development – 13166 (2 hrs/week; 2 CP; Fall 2025) A. Schier , Grayson Camp This course explores the fundamental processes by which cells, tissues, and organisms develop and change over time, from…


Adipose tissue as a culprit: How obesity leads to diabetes

Diabetes is a medical condition in which the body is unable to keep blood sugar in a healthy range. Normally, the pancreas produces sufficient insulin to regulate the blood sugar level and maintain homeostasis. However, in…


Projects

Research projects We investigate the physiology of bacterial pathogens ( Salmonella , Pseudomonas , Staphylococcus ) in infected rodent and human tissues, focusing on single-cell behavior and potential applications for novel…


Biozentrum Highlights 2022

After more than two years of the Covid pandemic, research and life at the Biozentrum have largely returned to normal. This extraordinary time has taught us that much can be replaced by virtual formats, but face-to-face…


Precise Genetics: New CRISPR method enables efficient DNA modification

With the revolutionary CRISPR/Cas technology, the DNA of living organisms can be precisely altered. Using a guide RNA that recognizes a specific DNA sequence, Cas9 protein is recruited to that sequence and cuts the DNA. This…


How does a wing grow? A journey on the path of proteins.

How organs develop and how they grow to the right size and shape are fundamental questions in developmental biology. The morphogen Dpp is a signaling molecule controlling the development of different organs with regard to…


One or the other: Why strength training might come at the expense of endurance muscles

Fitness clubs are booming: New gyms are springing up like mushrooms. More and more people are striving to build up and strengthen their muscles. But what exactly happens in the muscle during training? In their recent work,…


Randy Schekmann

Speaking from the soapbox November 2014 Brisk and sometimes bracing walks from his flat to and from the Biozentrum - this is the first thing that comes to mind to the famous Californian. In the early 1980ies the Nobel Prize…


New target to treat severe autoimmune disease

LRBA deficiency is a rare and severe autoimmune disorder that was first described in 2012. This disease is caused by a genetic defect in the LRBA gene and is characterized by an impaired immune response and autoimmunity.…


Sleep-wake rhythm: Fish change our understanding of sleep regulation

Until recently, it was assumed that vertebrates share similar mechanisms controlling sleep behavior. That's why researchers have been using fish in the past 20 years as a model organism to study sleep and its regulation. Now…