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New method: Small cell organelles make it big

Although cells are separated from the outside world by a membrane, they can still sense well what is happening around them. They capture hormones and nutrients such as sugar, iron or cholesterol and bring them packed in…


Genetic engineering in research: same same, but different

The cell envelope is covered with a wide variety of receptor proteins. They are the sensors to the environment, perceive signals such as the availability of nutrients and transmit this information to the inside of the cell.…


Multiple treatments to slow age-related muscle wasting

We now live longer than at any point in human history, but to enjoy those extra years, we need to remain healthy, mobile and independent. With age, however, our muscles inevitably lose mass and strength. This age-related…


Bacterial nanosized speargun works like a power drill

Millions of tiny microbes on leaves, stones or our skin jostle for space. And almost everywhere they have to compete for resources and nutrients. In the course of evolution, some bacteria have therefore developed a weapon to…


How the key protein mTOR controls cell growth

Cells proliferate by dividing repeatedly. Each cell division produces two daughter cells, which must first grow to a certain size before they can divide, too. This requires an increased production of cell components,…


Liver cancer: Lipid synthesis promotes tumor formation

In Switzerland, about 650 new cases of liver cancer are diagnosed every year. The incidence of the malignant and aggressive liver cell carcinoma has doubled in the last 20 years, especially in developed countries. One…


Cell receptors: of voids and void fillers

The G protein-coupled receptors (GPCRs) perform very diverse tasks in our body. They enable us to see, taste food, feel cold or warm, or respond to stress. Located on the cell surface, GPCRs sense a large variety of signals…


Liver cancer: How liver cells go astray

The causes of liver cancer are manifold. In addition to metabolic disorders such as those associated with obesity, the main causes in the western world are infections with hepatitis C virus and high alcohol consumption.…


Lab-on-a-chip for tracking single bacterial cells

It is hardly bigger than a matchbox and yet there is a laboratory en miniature on this chip. Single bacterial cells grow in about 2000 channels of a thousandth of a millimeter in diameter and can be individually studied in…


New vaccine concept tackles harmful bacteria in the intestine

The issue of intestinal bacteria is a complex one. On the one hand, we are dependent on the microorganisms because they are the ones that digest the food in our intestine. On the other hand, there are also numerous pathogens…