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CV

CV of Prof. Dr. Christoph Handschin ORCID 0000-0003-0603-1097 Google Scholar Google Scholar Nationality Swiss Positions: Since 2015 Full Professor in Pharmacology (tenured), Biozentrum, University of Basel, Switzerland 2009…


Precise Genetics: New CRISPR method enables efficient DNA modification

With the revolutionary CRISPR/Cas technology, the DNA of living organisms can be precisely altered. Using a guide RNA that recognizes a specific DNA sequence, Cas9 protein is recruited to that sequence and cuts the DNA. This…


Emeriti

Emeriti Prof. Dr. Ueli Aebi, Emeritus 1986 – 2011 Professor of Structural Biology Emeritus page Prof. Dr. Werner Arber, Emeritus 1971 – 1996 Professor of Molecular Microbiology Emeritus page Prof. Dr. Yves-Alain Barde,…


Awards for Biozentrum junior researchers

Young scientists make a major contribution to research: They are the foundation, innovative force and future of universities and research institutions. Almost half of the staff at the Biozentrum are PhD students and…


Farewell of Prof. Martin Spiess

A farewell event will be held on June 4, 2021, at 4 p.m. in honor of Martin Spiess, who has been Professor of Biochemistry at the Biozentrum since 1986. The program includes a welcome speech as well as words of thanks by the…


How does Parkinson's disease develop? Study raises doubts on a previous theory of Parkinson’s disease

The arms and legs tremble incessantly, the muscles become weaker and the movements slower − these are typical symptoms that many Parkinson's patients suffer from. More than six million people are affected worldwide. In these…


Like an assembly line: Molecular factories produce bioactive compounds

Cholesterol-lowering agents, antihypertensives or malaria medications, cancer drugs and antibiotics - many of our current drugs are based on natural products. Bacteria and fungi actually produce these chemical substances in…


How bacteria reinforce their protective shield against stress

When infecting a host, pathogens not only need to evade the immune defense but also to survive diverse living conditions, such as the acidic conditions in the stomach or the salty intestinal environment. Gram negative…


Acrobatic duo in the cells

Misfolded proteins are non-functional and cause cell damage. In order to prevent this, there is a whole arsenal of proteins – called chaperones – that assist with folding and carry out quality control. In the bacterium…


Like a zipper – How cells form new blood vessels

The blood vessels form a widely ramified supply system that passes through our body from head to toe. They serve as pathways for blood cells and transport oxygen as well as nutrients into each individual organ. In the…