With the revolutionary CRISPR/Cas technology, the DNA of living organisms can be precisely altered. Using a guide RNA that recognizes a specific DNA sequence, Cas9 protein is recruited to that sequence and cuts the DNA. This…

Pioneers The transcription factors that specific cell fates Our body consists of 30 trillion cells that are organized into organs such as the liver, heart and kidneys. These specialized cells are generated in the embryo by a…

Breast cancer is by far the most frequent type of cancer affecting women and a leading cause of death, despite advances in its detection and treatment. There are different forms of breast cancer and the causes are just as…

Individual visual stimuli are not processed independently by our brain. Rather neurons exchange incoming information to form a coherent perceptual image from the myriad of visual details impinging on our eyes. How our visual…

CV of Prof. Dr. Christoph Handschin ORCID 0000-0003-0603-1097 Google Scholar Google Scholar Nationality Swiss Positions: Since 2015 Full Professor in Pharmacology (tenured), Biozentrum, University of Basel, Switzerland 2009…

Nikon Ti2 "seqFISH" LOCATION: Room 07.057 SPECIFICATIONS: Imaging: very flexible and stable inverted widefield microscope Stand: Ti2-E Inverted with perfect focus and large field of view (F-mount) XY-stage: fully motorized…

A farewell event will be held on June 4, 2021, at 4 p.m. in honor of Martin Spiess, who has been Professor of Biochemistry at the Biozentrum since 1986. The program includes a welcome speech as well as words of thanks by the…

Young scientists make a major contribution to research: They are the foundation, innovative force and future of universities and research institutions. Almost half of the staff at the Biozentrum are PhD students and…

The arms and legs tremble incessantly, the muscles become weaker and the movements slower − these are typical symptoms that many Parkinson's patients suffer from. More than six million people are affected worldwide. In these…

Cholesterol-lowering agents, antihypertensives or malaria medications, cancer drugs and antibiotics - many of our current drugs are based on natural products. Bacteria and fungi actually produce these chemical substances in…