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Artificial Intelligence Tools shed light on millions of proteins

In the past years, AlphaFold has revolutionised protein science. This Artificial Intelligence (AI) tool was trained on protein data collected by life scientists for over 50 years, and is able to predict the 3D shape of…


Summer Vacation in the Lab

25 students from Basel-Stadt and Basel-Land secured one of the few places at the Basel Summer Science Academy 2024 at the Biozentrum. The program was established in 2019 to give high school students insight into the research…


How bacteria reinforce their protective shield against stress

When infecting a host, pathogens not only need to evade the immune defense but also to survive diverse living conditions, such as the acidic conditions in the stomach or the salty intestinal environment. Gram negative…


Molecular bodyguards against Parkinson's disease

Parkinson's disease is one of the most common neurodegenerative disorders. In Switzerland, about 15,000 people are affected. Because of the worldwide rise in life expectancy, a rapid increase in Parkinson's cases is expected…


Like a zipper – How cells form new blood vessels

The blood vessels form a widely ramified supply system that passes through our body from head to toe. They serve as pathways for blood cells and transport oxygen as well as nutrients into each individual organ. In the…


Acrobatic duo in the cells

Misfolded proteins are non-functional and cause cell damage. In order to prevent this, there is a whole arsenal of proteins – called chaperones – that assist with folding and carry out quality control. In the bacterium…


Engineered enzymes: String pullers in cell communication

Cells are the building blocks of all living creatures. In order to form a complex organism and stay healthy, cells need to communicate with each other and integrate the response within themselves. A group of enzymes,…


Patricia Marini

Testimonial of Patricia Marini University of Basel, Switzerland, Research Group Dirk Bumann Where are you from and what are you studying? I’m from Rheinfelden in Germany, just over the border, and study molecular biology at…


Gabriele Pumo

Testimonial of Gabriele Pumo University of Basel, Switzerland, Research Group Markus Affolter Where do you come from and what do you study? I come from the Ticino, the Italian speaking part of Switzerland, and have just…


Oliver Biehlmaier

Oliver Biehlmaier, Head of Imaging Core Facility For 14 years, the Biozentrum has had its Imaging Core Facility (IMCF) – and for 14 years, it has been led by Oliver Biehlmaier. The IMCF was among the first technology…