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Development of a novel class of antibiotics

A number of pathogens protect themselves with an outer membrane that makes it difficult to combat them with antibiotics. In addition, the widespread use of antibiotics promotes the development of resistant bacteria. In…


How pathogens switch on their virulence

Since the late 20th century, diseases that are transmitted from animals to humans, so-called zoonoses, have been on the rise. One of these is leptospirosis, an infectious disease that is becoming more common due to climate…


Novel antibiotic deceives bacteria through mimicry

An increasing number of bacterial pathogens are resistant to antibiotics. And the most dangerous pathogens share a common feature: a double membrane that is difficult to penetrate. Even when antibiotic agents are able to…


How bacteria reinforce their protective shield against stress

When infecting a host, pathogens not only need to evade the immune defense but also to survive diverse living conditions, such as the acidic conditions in the stomach or the salty intestinal environment. Gram negative…


Inspiring Biozentrum Symposium 2020

The Biozentrum organizes a symposium for its employees and students annually. This provides an insight into other areas of research, as well as an overview of the many projects being carried out. Furthermore, the symposium…


Testing

Pseudocontact Shifts in Biomolecular NMR Spectroscopy Thomas Müntener, Daniel Joss, Daniel Häussinger*, and Sebastian Hiller* Paramagnetic centers in biomolecules, such as specific metal ions that are bound to a protein,…


A new springboard into research for Bachelor students at the Biozentrum

What questions arise in day-to-day scientific research? How is it to work as a scientist? And how does a research group work? The opportunity to get to the bottom of these questions, to actively participate in everyday…


Structural Biology, Biochemistry and Biophysics

Structural Biology, Biochemistry and Biophysics Prof. Jan Pieter Abrahams Uncovering the fundamental shapes of life Prof. Marek Basler Unraveling the secrets of bacterial injection needles Prof. Christoph Dehio Molecular…


Physics of Life

Physics of Life Prof. Jan Pieter Abrahams Uncovering the fundamental shapes of life Prof. Attila Becskei Mechanisms controlling gene regulatory networks Prof. David Brückner Physical principles of living systems Prof. Knut…


Chronology

2026 Prof. Sebastian Hiller Member of the European Molecular Biology Organization (EMBO) News Weblink Prof. Sebastian Hiller Member of the German National Academy of Sciences Leopoldina News Weblink Prof. Fiona Doetsch…