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Tackling the Achilles' heel of pneumonia-causing bacteria

According to the WHO, more than one million people worldwide die of pneumococcal infections every year. Young children, elderly and immunocompromised persons are particularly affected. After the introduction of…


Virulence could be the Achilles heel of pathogens

Bacteria are masters of survival. Pathogens, for example, produce a range of molecules enabling them to infect their hosts and to evade the immune defense. The entero-pathogenic bacterium Salmonella enterica Typhimurium uses…


About the Biozentrum

About the Biozentrum What is the Biozentrum and what are its main research areas? The Biozentrum of the University of Basel is a world leading life sciences institute, with a focus on molecular and cellular biology. Find out…


Thomas Müller

Getting the point in science. May 2014 “Shhhh. It’s news time!” – That’s what children used to hear at lunch time. This family tradition has been lost over the years. But not so the broadcast of the Swiss Radio main news at…


ERC - SPLICECODE

SPLICECODE - Alternative Splicing Codes for Synaptic Specificity The SPLICECODE project funded by an Advanced Grant from the European Research Council explore the hypothesis that alternative splicing is a central mechanism…


In double pack – paired proteins give you wings

From fingers on our hands to the wings of insects, the bodies of different animals form limbs of various shapes and sizes. Morphogens are signaling molecules that provide the necessary information for the proper development…


New insights challenge previous views about a muscle growth factor

While Myc concentrations in muscle are normally low, they rise with growth stimuli, such as exercise. Based on this observation and the fact that Myc stimulates many growth processes, researchers hypothesized that Myc was…


Nina Beutling

Testimonial Nina Beutling University of Basel, Research Group Attila Becskei Why did you apply for the Biozentrum Research Summer? Studying biology is my second course of studies. I am a primary school teacher and still…


Heat stress reduces lifetime of mRNA molecules

The coronavirus pandemic and the development of the novel vaccines has brought mRNA into the public eye. mRNAs are transcripts of DNA. They serve as a template for protein production and are degraded after a certain time.…


Cell receptors: of voids and void fillers

The G protein-coupled receptors (GPCRs) perform very diverse tasks in our body. They enable us to see, taste food, feel cold or warm, or respond to stress. Located on the cell surface, GPCRs sense a large variety of signals…