Simply grasping a coffee cup needs fine motor coordination with the highest precision. This required performance of the brain is an ability that can also be learned and trained. Prof. Kelly Tan's research group at the…
Individual visual stimuli are not processed independently by our brain. Rather neurons exchange incoming information to form a coherent perceptual image from the myriad of visual details impinging on our eyes. How our visual…
When our innate immune system detects a pathogen it mounts a potent inflammatory response that has the capacity to contain and eliminate the infection, but typically also causes significant damage to the inflamed tissue.…
If a cell encounters a stress situation, whether it is due to nutrient restriction or osmotic shock, the cell reacts immediately to ensure its survival. Prof. Anne Spang’s research group at the Biozentrum of the University…
In the past, amyloids have mainly been associated with neurodegenerative diseases. These solid, insoluble protein clumps damage the nerve cells. The research group led by Prof. Martin Spiess at the Biozentrum of the…
Cells live and survive by taking up proteins, recycling and reusing or degrading them. The proteins are located on the cell surface and are transported from here into the cell’s interior. About 80 percent of these membrane…
From tackling nosocomial pathogens to decoding memory storage, Biozentrum scientists made significant advances in the past year. Prof. Urs Jenal’s team, for example, revealed how Pseudomonas aeruginosa exploits goblet cells…
Michelle Gut, PhD student, group Maria Hondele What inspired you to pursue a career in science? Already back in high school, I loved the STEM subjects. At fifteen, I took a bold step and moved out from home to pursue an…
Genetic information is protected in the cell nucleus by a membrane that contains numerous nuclear pores. These pores facilitate the traffic of proteins known as importins that deliver molecular cargoes between the nucleus…
With the revolutionary CRISPR/Cas technology, the DNA of living organisms can be precisely altered. Using a guide RNA that recognizes a specific DNA sequence, Cas9 protein is recruited to that sequence and cuts the DNA. This…
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