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Dimitris Koufopoulos

Testimonial of Dimitris Koufopoulos University of Aberdeen, Scotland, Research Group Christoph Handschin Where do you come from and what do you study? I am from Greece and study Biomedical Sciences at the University of…


Precise Genetics: New CRISPR method enables efficient DNA modification

With the revolutionary CRISPR/Cas technology, the DNA of living organisms can be precisely altered. Using a guide RNA that recognizes a specific DNA sequence, Cas9 protein is recruited to that sequence and cuts the DNA. This…


Emeriti

Emeriti Prof. Dr. Ueli Aebi, Emeritus 1986 – 2011 Professor of Structural Biology Emeritus page Prof. Dr. Werner Arber, Emeritus 1971 – 1996 Professor of Molecular Microbiology Emeritus page Prof. Dr. Yves-Alain Barde,…


The power of neighbors: Neighboring synapses shape learning and memory

In 1949, the Canadian psychologist Donald O. Hebb described that connections between neurons become stronger when the neurons are active at the same time, and that strengthened connections facilitate signal transmission. The…


Genetic signature boosts protein production during cell division

The production of proteins is the most energy-consuming activity of cells. It needs to be tightly regulated, to ensure efficient use of cellular resources. Researchers led by Prof. Mihaela Zavolan at the Biozentrum have now…


Aging muscles – uncovering the causes of sarcopenia

You are likely to lose around one third of your muscle mass over your lifetime. An excessive loss of muscle mass and muscle strength is known as sarcopenia. As life expectancy increases, so does the number of people…


Good times, bad times: Worms equip their offspring for the future

Food scarcity, toxins, or pathogens: to survive, organisms must be able to respond to diverse environmental conditions and adapt their behavior appropriately. Parents pass on information about the prevailing living…


Nanocontainers introduced into the nucleus of living cells

In order to combat diseases, different therapies strive to intervene in pathological processes that occur in the cell nucleus. Chemotherapies, for example, target biochemical reactions that are involved in the proliferation…


Architecture of cellular control center mTORC2 elucidated

The protein complex mTORC2 plays a crucial role in the regulation of cellular metabolism. It stimulates, for example, the production of lipids and fatty acids, but it also controls carbohydrate metabolism. In the past,…


Survival strategy of messenger RNAs during cellular sugar shortage

If a cell encounters a stress situation, whether it is due to nutrient restriction or osmotic shock, the cell reacts immediately to ensure its survival. Prof. Anne Spang’s research group at the Biozentrum of the University…