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Cancer research: Metabolite drives tumor development

The liver is a vital organ with many important functions in the body. It metabolizes nutrients, stores energy, regulates the blood sugar level and plays a crucial role in detoxifying and removing harmful components and…


A “Catch-22” vaccine against Salmonellosis

Antibiotics are still the treatment of choice in fighting bacterial infections. However, due to their extensive and sometimes improper use in medicine and livestock farming, resistant pathogens are increasingly emerging,…


Researchers crack a puzzle of bacterial genome evolution

The forefather of phylogenetic trees can be found in Charles Darwin's revolutionary work "On the Origin of Species". These trees provide information about the evolution and relationships of species, from simple cells to…


Tackling the Achilles' heel of pneumonia-causing bacteria

According to the WHO, more than one million people worldwide die of pneumococcal infections every year. Young children, elderly and immunocompromised persons are particularly affected. After the introduction of…


Genetic engineering in research: same same, but different

The cell envelope is covered with a wide variety of receptor proteins. They are the sensors to the environment, perceive signals such as the availability of nutrients and transmit this information to the inside of the cell.…


Multiple treatments to slow age-related muscle wasting

We now live longer than at any point in human history, but to enjoy those extra years, we need to remain healthy, mobile and independent. With age, however, our muscles inevitably lose mass and strength. This age-related…


New method: Small cell organelles make it big

Although cells are separated from the outside world by a membrane, they can still sense well what is happening around them. They capture hormones and nutrients such as sugar, iron or cholesterol and bring them packed in…


Virulence could be the Achilles heel of pathogens

Bacteria are masters of survival. Pathogens, for example, produce a range of molecules enabling them to infect their hosts and to evade the immune defense. The entero-pathogenic bacterium Salmonella enterica Typhimurium uses…


Bacterial nano-speargun as a precision weapon

No matter where you go, you always find someone there already. This is true for many living creatures but especially for bacteria. In order to be able to stand their ground and eliminate unwanted rivals, many bacteria rely…


Bacterial nanosized speargun works like a power drill

Millions of tiny microbes on leaves, stones or our skin jostle for space. And almost everywhere they have to compete for resources and nutrients. In the course of evolution, some bacteria have therefore developed a weapon to…