In modern medicine, personalized therapies are becoming increasingly important – particularly in the treatment of genetic diseases. One such promising approach is the use of so-called antisense oligonucleotides (ASOs). These…
Blood vessels run throughout the entire body, delivering nutrients and oxygen through the circulating blood. During vessel formation, cells first form local lumens, which then fuse to form a continuous tubular network. The…
In recent years, the growing threat of antimicrobial resistance has become widely recognized. However, much less is known about drug-tolerant pathogens, which also complicate the treatment of bacterial infections. These…
In Switzerland, it is not uncommon for a patient to develop an infection during a hospital stay. One reason for this is insufficient hygiene, as shown recently in a study by the Swiss Agency for Therapeutic Products,…
The forefather of phylogenetic trees can be found in Charles Darwin's revolutionary work "On the Origin of Species". These trees provide information about the evolution and relationships of species, from simple cells to…
Antibiotics are still the treatment of choice in fighting bacterial infections. However, due to their extensive and sometimes improper use in medicine and livestock farming, resistant pathogens are increasingly emerging,…
Our cells continuously receive external signals, which are transmitted across the cell membrane into the cell, to be processed in the cell nucleus. Various signaling pathways are found in the cell membrane. One is the…
How organs develop and how they grow to the right size and shape are fundamental questions in developmental biology. The morphogen Dpp is a signaling molecule controlling the development of different organs with regard to…
Infections such as tuberculosis or typhoid fever are caused by bacteria and can usually be treated well with antibiotics, at least as long as the bacteria are not resistant. However, full eradication of the bacteria cannot…
The liver is a vital organ with many important functions in the body. It metabolizes nutrients, stores energy, regulates the blood sugar level and plays a crucial role in detoxifying and removing harmful components and…
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