Bartonella are bacteria that can cause diverse infectious diseases in man, such as cat-scratch disease. In order to prevent the accumulation of mutations during the infection cycle, pathogens require efficient DNA repair…
Sleep is universal and essential: not only humans, but even flies and jellyfish sleep for a significant portion of the day. Like eating or mating, sleep is also controlled by motivational drives. Our drive to sleep increases…
In modern medicine, personalized therapies are becoming increasingly important – particularly in the treatment of genetic diseases. One such promising approach is the use of so-called antisense oligonucleotides (ASOs). These…
Blood vessels run throughout the entire body, delivering nutrients and oxygen through the circulating blood. During vessel formation, cells first form local lumens, which then fuse to form a continuous tubular network. The…
In recent years, the growing threat of antimicrobial resistance has become widely recognized. However, much less is known about drug-tolerant pathogens, which also complicate the treatment of bacterial infections. These…
In Switzerland, it is not uncommon for a patient to develop an infection during a hospital stay. One reason for this is insufficient hygiene, as shown recently in a study by the Swiss Agency for Therapeutic Products,…
The forefather of phylogenetic trees can be found in Charles Darwin's revolutionary work "On the Origin of Species". These trees provide information about the evolution and relationships of species, from simple cells to…
Antibiotics are still the treatment of choice in fighting bacterial infections. However, due to their extensive and sometimes improper use in medicine and livestock farming, resistant pathogens are increasingly emerging,…
Our cells continuously receive external signals, which are transmitted across the cell membrane into the cell, to be processed in the cell nucleus. Various signaling pathways are found in the cell membrane. One is the…
How organs develop and how they grow to the right size and shape are fundamental questions in developmental biology. The morphogen Dpp is a signaling molecule controlling the development of different organs with regard to…
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