Human Frontier Science Program: In search of conserved mRNA localization and anchoring mechanisms We have started a new international collaborative program with Prof. Chris Brown (University of Otago, Dunedin, New Zealand)…
Muscle aging Rapid advances in treating life-threatening, age-related diseases, such as cancer and cardiovascular disease, have extended human lifespan in many developed countries. However, greater longevity has meant more…
Principles of intracellular organization Correct intracellular localization of proteins and mRNA ensures cell survival. Specific localization of these molecules allows the development of multicellular organisms such as…
Leica Viventis SCAPE LOCATION: Room 07.081 SPECIFICATIONS: Single objective lightsheet based in OPM/SCAPE technology DMi8 stand with LMT200-T high-precision scanning stage K3M camera for widefield sCMOS Kinetix 22 cameras…
Publication list - curated & annotated Recent highlights Bacteria use a general danger signal to trigger biofilm formation - Nature Microbiology 2025 Mechanical properties of biofilms measured with spatial resolution -…
TOR signaling and control of cell growth Fig. 1: Architecture of human mTOR complex 1 Introduction Cell growth is highly regulated. Cells respond to nutrients or other appropriate growth stimuli by up-regulating…
Principles of intracellular organization Asymmetry is an inherent property of most cells. Proteins and mRNA have to be distributed at specific cellular locales to perform their assigned function or to be translated in a…
Gene expression regulatory programs Although the genetic material is more or less identical in all cells of our body, which genes are being “read” and how they are read to produce RNAs and proteins varies between cell types.…
Leica LMD7 Laser Micro-Dissection Microscope LOCATION: Room 07.090 SPECIFICATIONS: Leica LMD7 is a laser microdissection system enabling users to isolate specific single cells or entire areas of tissue. contact-free and…
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