Membrane proteins are a basic component of each individual cell of the human body and play a vital role in the cell’s structure, metabolism and transport. They ensure that many substances, such as hormones and other…
In mammals, movement is controlled by circuits spanning throughout the central nervous system from the cortex to the spinal cord. The role of motor cortex in the control of movement is still unclear. In humans, lesions to…
Simply grasping a coffee cup needs fine motor coordination with the highest precision. This required performance of the brain is an ability that can also be learned and trained. Prof. Kelly Tan's research group at the…
When pathogens infect an organism, the defense system immediately starts to fight the bacteria. To escape the patrolling immune cells, some bacteria invade and replicate inside host cells. However, the host has developed…
Since his time as a postdoctoral fellow at Harvard Medical School in Boston, Marek Basler has been fascinated by a tiny bacterial injection apparatus, the so-called type 6 secretion system (T6SS). This nanomachine works like…
Genetic information is protected in the cell nucleus by a membrane that contains numerous nuclear pores. These pores facilitate the traffic of proteins known as importins that deliver molecular cargoes between the nucleus…
Individual visual stimuli are not processed independently by our brain. Rather neurons exchange incoming information to form a coherent perceptual image from the myriad of visual details impinging on our eyes. How our visual…
Our brain generates new neurons throughout life. A diversity of stimuli promotes stem cells in their niche to form neurons that migrate to their place of action. In an animal model Prof. Fiona Doetsch’s team at the…
With the revolutionary CRISPR/Cas technology, the DNA of living organisms can be precisely altered. Using a guide RNA that recognizes a specific DNA sequence, Cas9 protein is recruited to that sequence and cuts the DNA. This…
In 1949, the Canadian psychologist Donald O. Hebb described that connections between neurons become stronger when the neurons are active at the same time, and that strengthened connections facilitate signal transmission. The…
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