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Architecture of cellular control center mTORC2 elucidated

The protein complex mTORC2 plays a crucial role in the regulation of cellular metabolism. It stimulates, for example, the production of lipids and fatty acids, but it also controls carbohydrate metabolism. In the past,…


Genetic signature boosts protein production during cell division

The production of proteins is the most energy-consuming activity of cells. It needs to be tightly regulated, to ensure efficient use of cellular resources. Researchers led by Prof. Mihaela Zavolan at the Biozentrum have now…


Nanocontainers introduced into the nucleus of living cells

In order to combat diseases, different therapies strive to intervene in pathological processes that occur in the cell nucleus. Chemotherapies, for example, target biochemical reactions that are involved in the proliferation…


Good times, bad times: Worms equip their offspring for the future

Food scarcity, toxins, or pathogens: to survive, organisms must be able to respond to diverse environmental conditions and adapt their behavior appropriately. Parents pass on information about the prevailing living…


Aging muscles – uncovering the causes of sarcopenia

You are likely to lose around one third of your muscle mass over your lifetime. An excessive loss of muscle mass and muscle strength is known as sarcopenia. As life expectancy increases, so does the number of people…


The power of neighbors: Neighboring synapses shape learning and memory

In 1949, the Canadian psychologist Donald O. Hebb described that connections between neurons become stronger when the neurons are active at the same time, and that strengthened connections facilitate signal transmission. The…


Michael Hall receives the 2019 Nakasone Award

The 2019 Nakasone Award was announced during the World Conference of Science Journalists in Lausanne, on Tuesday 2th July. “Michael Hall’s groundbreaking work expands the frontiers of science and enables us to begin to…


Nanomachine keeps cellular power plants healthy

Every single cell of our body contains hundreds of tiny power plants, the mitochondria, which produce the energy required by the body, whether it be for walking, digesting or to ponder ideas. This inevitably generates…


Engineered enzymes: String pullers in cell communication

Cells are the building blocks of all living creatures. In order to form a complex organism and stay healthy, cells need to communicate with each other and integrate the response within themselves. A group of enzymes,…


Acrobatic duo in the cells

Misfolded proteins are non-functional and cause cell damage. In order to prevent this, there is a whole arsenal of proteins – called chaperones – that assist with folding and carry out quality control. In the bacterium…