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Damaged but not defeated: Bacteria use nano-spearguns to retaliate against attacks

In the world of microbes, peaceful coexistence goes hand in hand with fierce competition for nutrients and space. Certain bacteria outcompete rivals and fend off attackers by injecting them with a lethal cocktail using tiny,…


New way to improve the efficacy of innovative RNA therapies

In modern medicine, personalized therapies are becoming increasingly important – particularly in the treatment of genetic diseases. One such promising approach is the use of so-called antisense oligonucleotides (ASOs). These…


The changing brain: exploring the evolution and plasticity of neural circuits in salamanders

The changing brain: exploring the evolution and plasticity of neural circuits in salamanders How nervous systems diversified over millions of years of evolution to adapt to changing environments remains one of the biggest…


Quantitative tissue analysis at the Translational Spatial Profiling Center (TSPC)

Quantitative tissue analysis at the Translational Spatial Profiling Center (TSPC) Denis Schapiro (Heidelberg University Hospital) specializes in spatial omics and highly multiplexed imaging to profile single cells within…


Spatial Sequencing of Host-Microbiome Interactions

Spatial Sequencing of Host-Microbiome Interactions Microbe-microbe and host–microbe interactions are central to the functioning of the human microbiome, but few tools are available to measure these interactions spatially…


Multi-spine plasticity and its origin in molecular dynamics

Multi-spine plasticity and its origin in molecular dynamics Abstract: Synaptic plasticity is traditionally viewed as a localized event taking place at a single synapse. Yet growing experimental evidence indicates that this…


BacFighT6

BacFighT6 Simulation of T6SS-mediated Bacterial Interactions The purpose of this simulation is to showcase various aspects of bacterial interactions mediated by the Type VI secretion system. For the latest version,…


Survival trick: Pathogen taps iron source in immune cells

Our body keeps bacterial pathogens under control by restricting their access to essential nutrients such as iron. Iron is crucial for all living organisms. When bacteria are deprived of iron, they stop growing and…


Slow-growing bacteria respond more sensitively to their environment

Researchers led by Prof. Erik van Nimwegen at the Biozentrum, University of Basel have discovered a new mechanism in bacteria that controls their response to prevailing environmental conditions. They derived their theory…


Venue and travel information

Venue and travel information History of Monte Verità In 1900 a group of idealists from Northern Europe settled on the hilltop above Ascona. Their vision was to start a new life, an ideal society based on freedom, simplicity,…