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Cholesterol disrupts lipid metabolism in the cell

Our cells continuously receive external signals, which are transmitted across the cell membrane into the cell, to be processed in the cell nucleus. Various signaling pathways are found in the cell membrane. One is the…


Laura de Smalen

Laura de Smalen, PhD Student, Group Handschin Why did you decide to do a PhD? During my bachelor's in Nutrition and Dietetics, I developed a strong interest in the causes and mechanisms that underlie the human diseases that…


Projects

Nuclear magnetic resonance spectroscopy of biomolecules We apply and develop high-resolution Nuclear Magnetic Resonance (NMR) methods to elucidate structure, function, and dynamics of biological macromolecules. The…


Discovery of a new antibiotic against resistant pathogens

The WHO calls the creeping and rapidly growing number of antibiotic-resistant bacteria a “silent pandemic”. The crisis is aggravated by the fact that hardly any new drugs have come onto the market in recent decades. Even…


J.C.W. Shepherd Prize

J.C.W. Shepherd PhD Student Prize of the Biozentrum, University of Basel Background The wife of John Charles Warren Shepherd, a former collaborator of Walter Gehring (see Shepherd JC et al. 1984 Nature, Shepherd JC et al.…


Projects

Cell signaling and dynamics in bacterial growth, adaptation, and persistence Our studies aim at understanding the molecular and cellular principles involved in the growth, differentiation and behavior of bacterial cells. We…


CV

CV of Prof. Dr. Markus Affolter ORCID 0000-0002-5171-0016 Nationality : Swiss Positions: Since 2005 Ordinarius, Developmental Biology, Biozentrum 2009 – 2010 Deputy Director of the Biozentrum 2000 – 2005 Assistant Professor,…


Virtual Biozentrum Symposium 2021

The restrictions resulting from the ongoing coronavirus pandemic impact each of us in our daily work. But the crisis also sparks resourcefulness. The Biozentrum Symposium, for example, was completely re-designed and moved to…


Keep on moving: Sports relieve tumor-associated anemia

The two major symptoms of cancer are muscle atrophy (loss of muscle mass) and anemia (reduced hemoglobin level), leading to weight loss, fatigue, lethargy and reduced physical performance. Moreover, both are also symptoms…


Two SNSF Ambizione Fellowships for the Biozentrum

Alexander Harms, project leader in Urs Jenal's group, is one of the two SNSF Ambizione Fellows. He studied at the Biozentrum of the University of Basel and earned his PhD in the group of Prof. Christoph Dehio. In 2015, the…