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Projects

Principles of intracellular organization Asymmetry is an inherent property of most cells. Proteins and mRNA have to be distributed at specific cellular locales to perform their assigned function or to be translated in a…


PhD Fellows

PhD Fellows 2023 Aleksandr Kuznetsov Group Neher R. Biozentrum, Room: 08.Q3 aleksandr.kuznetsov unibas ch Jiangning Li 3. Rotation Group Diard M. Biozentrum, Room: 09.Q3 jiangning.li unibas ch Daniil Litvinov Group Schwede…


Projects

We study the cellular organization and regulation of metabolism by large macromolecular assemblies as well as giant microbial biosynthetic assembly lines. Our research builds on hybrid use of state-of-the-art cryo electron…


Research Group Mihaela Zavolan

Gene expression regulatory programs Although the genetic material is more or less identical in all cells of our body, which genes are being “read” and how they are read to produce RNAs and proteins varies between cell types.…


Zeiss "LSM800 Inverted"

ZEISS POINT SCANNING CONFOCAL “LSM800 Inverted“ LOCATION: Room 07.092 SPECIFICATIONS: Imaging: Confocal for fixed and large samples Stand: Zeiss Axio Observer 2 GaAsP PMT detectors, no transmitted light PMT XY-stage:…


Zeiss "LSM700 Upright"

ZEISS POINT SCANNING CONFOCAL “LSM700 Upright“ LOCATION: Room 07.083 SPECIFICATIONS: Imaging: Confocal for fixed samples Stand: Zeiss Axio Imager XYZ-stage: fully motorized Software: Zen black 2010 OBJECTIVES Objective…


Zeiss "LSM880 Inverted"

ZEISS POINT SCANNING CONFOCAL “LSM880 Inverted“ WITH AIRYSCAN LOCATION: Room 07.083 SPECIFICATIONS: Imaging: Confocal for live; large samples; Airyscan Stand: Zeiss Axio Observer XYZ-stage: motorized Fully equipped for live…


Michael Hall awarded Sjöberg Prize 2020

The Sjöberg Prize honors scientist for pioneering research in the field of cancer research. Michael Hall, Biozentrum of the University of Basel, and Prof. David M. Sabatini, are jointly awarded for their discovery of the…


Leica "SP8" (BSL2)

LEICA POINT SCANNING CONFOCAL “SP8“ BioSafety Level 2 LOCATION: Room 09.171 SPECIFICATIONS: Imaging: Confocal for live imaging (L2) Stand: Leica DMI 6000B with adaptive focus XY-stage: motorized Equipped with 1 HyD and 2…


Nuclear export of single large ribosomal subunits and mRNA particle

Nuclear export of single large ribosomal subunits and mRNA particle This talk focuses on RNA export studied in vivo by single particle tracking and super resolution microscopy. (1) We analysed the export kinetics of single…