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Survival trick: Pathogen taps iron source in immune cells

Our body keeps bacterial pathogens under control by restricting their access to essential nutrients such as iron. Iron is crucial for all living organisms. When bacteria are deprived of iron, they stop growing and…


Blood vessel formation: how the vascular cells respond to blood pressure

Throughout our body there is a dense, widely ramified network of blood vessels. It is estimated to be about 150,000 kilometers in length. The vessels supply all cells, even those in most far away regions of the body with…


Neutralizing antibodies control bacterial infection

Bartonella are bacteria that are transmitted from blood-sucking insects to mammals, including humans. There they enter the red blood cells and cause various symptoms. An example of such a human infection with a worldwide…


Designed proteins to treat muscular dystrophy

Muscular dystrophy is a term used to describe many different muscular diseases caused by genetic defects. To date, there are no treatments available to stop disease progression. In their study, the scientists led by Prof.…


Tagged for arrest: “Barcode” determines receptor’s fate.

Odors, light, hormones and a tremendous variety of signaling molecules are recognized by a large family of cell receptors, known as G protein-coupled receptors (GPCRs). They are located on the cell surface and transduce…


Novel antibiotic deceives bacteria through mimicry

An increasing number of bacterial pathogens are resistant to antibiotics. And the most dangerous pathogens share a common feature: a double membrane that is difficult to penetrate. Even when antibiotic agents are able to…


Liver cancer: Lipid synthesis promotes tumor formation

In Switzerland, about 650 new cases of liver cancer are diagnosed every year. The incidence of the malignant and aggressive liver cell carcinoma has doubled in the last 20 years, especially in developed countries. One…


T cells: No time to die

Like human beings, every cell in our body tries to ward off death as long as it can. This is particular true for a specific type of immune cells, called T-lymphocytes, or T cells for short. These cells keep viruses,…


Liver cancer: How liver cells go astray

The causes of liver cancer are manifold. In addition to metabolic disorders such as those associated with obesity, the main causes in the western world are infections with hepatitis C virus and high alcohol consumption.…


Hall of fame

Name Achievements Position and Years Radu Cristian Leonte Developed IVA Prime, a tool for automated primer design in in vivo assembly cloning PhD Student Since 2025 Fengjie Wu SNF Ambizione Fellowship 2024 Project Leader…