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An enemy within: Pathogens hide in tissue

Infections such as tuberculosis or typhoid fever are caused by bacteria and can usually be treated well with antibiotics, at least as long as the bacteria are not resistant. However, full eradication of the bacteria cannot…


Cholesterol disrupts lipid metabolism in the cell

Our cells continuously receive external signals, which are transmitted across the cell membrane into the cell, to be processed in the cell nucleus. Various signaling pathways are found in the cell membrane. One is the…


A “Catch-22” vaccine against Salmonellosis

Antibiotics are still the treatment of choice in fighting bacterial infections. However, due to their extensive and sometimes improper use in medicine and livestock farming, resistant pathogens are increasingly emerging,…


Researchers crack a puzzle of bacterial genome evolution

The forefather of phylogenetic trees can be found in Charles Darwin's revolutionary work "On the Origin of Species". These trees provide information about the evolution and relationships of species, from simple cells to…


Living in Basel

Living and working in Basel Basel is one of the top fifteen cities with the highest quality of living worldwide according to the 2023 Mercer study . It is located in the heart of Europe and embedded in Europe’s most…


Living in Basel

Living and working in Basel Basel is one of the top fifteen cities with the highest quality of living worldwide according to the 2023 Mercer study . It is located in the heart of Europe and embedded in Europe’s most…


BC2 Seminar Autumn 2019

BC2 - Basel Computational Biology Seminar Series - Fall Semester 2019 16.09.2019 | Timothy Vaughan, ETH Zürich Timothy Vaughan Computational Evolution Department of Biosystems Science and Engineering, ETH Zürich Basel,…


Liver cancer: How liver cells go astray

The causes of liver cancer are manifold. In addition to metabolic disorders such as those associated with obesity, the main causes in the western world are infections with hepatitis C virus and high alcohol consumption.…


Cell receptors: of voids and void fillers

The G protein-coupled receptors (GPCRs) perform very diverse tasks in our body. They enable us to see, taste food, feel cold or warm, or respond to stress. Located on the cell surface, GPCRs sense a large variety of signals…


Discovery of a new antibiotic against resistant pathogens

The WHO calls the creeping and rapidly growing number of antibiotic-resistant bacteria a “silent pandemic”. The crisis is aggravated by the fact that hardly any new drugs have come onto the market in recent decades. Even…