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Reaching and Grasping – Learning fine motor coordination changes the brain

Simply grasping a coffee cup needs fine motor coordination with the highest precision. This required performance of the brain is an ability that can also be learned and trained. Prof. Kelly Tan's research group at the…


Magnesium deprivation stops pathogen growth

When pathogens infect an organism, the defense system immediately starts to fight the bacteria. To escape the patrolling immune cells, some bacteria invade and replicate inside host cells. However, the host has developed…


Marek Basler receives prestigious "ERC Consolidator Grant"

Since his time as a postdoctoral fellow at Harvard Medical School in Boston, Marek Basler has been fascinated by a tiny bacterial injection apparatus, the so-called type 6 secretion system (T6SS). This nanomachine works like…


Like a revolving door: How shuttling proteins operate nuclear pores

Genetic information is protected in the cell nucleus by a membrane that contains numerous nuclear pores. These pores facilitate the traffic of proteins known as importins that deliver molecular cargoes between the nucleus…


Synapses in the brain mirror the structure of the visual world

Individual visual stimuli are not processed independently by our brain. Rather neurons exchange incoming information to form a coherent perceptual image from the myriad of visual details impinging on our eyes. How our visual…


Distant brain regions selectively recruit stem cells

Our brain generates new neurons throughout life. A diversity of stimuli promotes stem cells in their niche to form neurons that migrate to their place of action. In an animal model Prof. Fiona Doetsch’s team at the…


Dimitris Koufopoulos

Testimonial of Dimitris Koufopoulos University of Aberdeen, Scotland, Research Group Christoph Handschin Where do you come from and what do you study? I am from Greece and study Biomedical Sciences at the University of…


Precise Genetics: New CRISPR method enables efficient DNA modification

With the revolutionary CRISPR/Cas technology, the DNA of living organisms can be precisely altered. Using a guide RNA that recognizes a specific DNA sequence, Cas9 protein is recruited to that sequence and cuts the DNA. This…


Emeriti

Emeriti Prof. Dr. Ueli Aebi, Emeritus 1986 – 2011 Professor of Structural Biology Emeritus page Prof. Dr. Werner Arber, Emeritus 1971 – 1996 Professor of Molecular Microbiology Emeritus page Prof. Dr. Yves-Alain Barde,…


The power of neighbors: Neighboring synapses shape learning and memory

In 1949, the Canadian psychologist Donald O. Hebb described that connections between neurons become stronger when the neurons are active at the same time, and that strengthened connections facilitate signal transmission. The…