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Cell receptors: of voids and void fillers

The G protein-coupled receptors (GPCRs) perform very diverse tasks in our body. They enable us to see, taste food, feel cold or warm, or respond to stress. Located on the cell surface, GPCRs sense a large variety of signals…


Discovery of a new antibiotic against resistant pathogens

The WHO calls the creeping and rapidly growing number of antibiotic-resistant bacteria a “silent pandemic”. The crisis is aggravated by the fact that hardly any new drugs have come onto the market in recent decades. Even…


T cells: No time to die

Like human beings, every cell in our body tries to ward off death as long as it can. This is particular true for a specific type of immune cells, called T-lymphocytes, or T cells for short. These cells keep viruses,…


Heat stress reduces lifetime of mRNA molecules

The coronavirus pandemic and the development of the novel vaccines has brought mRNA into the public eye. mRNAs are transcripts of DNA. They serve as a template for protein production and are degraded after a certain time.…


Liver cancer: Lipid synthesis promotes tumor formation

In Switzerland, about 650 new cases of liver cancer are diagnosed every year. The incidence of the malignant and aggressive liver cell carcinoma has doubled in the last 20 years, especially in developed countries. One…


Neuronal circuits for fine motor skills

Picking up a pen and writing our name or reaching for a fork to eat spaghetti with tomato sauce are things we take for granted. However, holding a pen properly or bringing spaghetti to the mouth without making a mess…


Georg Halder

Always driven by curiosity May 2016 As a teenager he translated hieroglyphics and built a liquid engine. Later, as a PhD student in Walter Gehring’s lab, he bred some weird flies with eyes on their legs. Georg Halder has…


Guidelines

IMCF guidelines 1. General booking Rules: The user can book a microscope only after having received the appropriate introduction. The instruments can be booked up to 14 days in advance. During daily working hours (9-17h),…


Biozentrum Discovery Seminar Series

Biozentrum Discovery Seminars Biozentrum Discovery (BZD) is a seminar series, which alternates between talks by renowned guest speakers and seminars given by graduate students and postdocs from the Biozentrum. Since its…


Instruments

Instruments The instruments shown below are available in the Biophysics Facility (BF) of the Biozentrum and can be booked and used by all members of the University of Basel, following training by BF staff. The instruments…