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Biozentrum again part of the largest EU-funded research project on autism

In 2012, the "European Autism Interventions - A Multicentre Study for Developing New Medications" (EU-AIMS) was launched as a collaboration for research for the treatment of autism. The aim of this collaboration is to…


German pharma company acquires Biozentrum start-up for 450 million Swiss francs

T3 Pharmaceuticals (“T3 Pharma”) was founded in 2015 as a spin-off of the Biozentrum of the University of Basel. The company focuses on bacterial therapies for the treatment of solid tumors. The Basel-based biotech company’s…


Lethal combination: Drug cocktail turns off the “juice” to cancer cells

The widely used anti-diabetes drug metformin not only reduces blood sugar but also has an anti-cancer effect. However, the metformin dose commonly used in the treatment of diabetes is too low to inhibit cancer growth. The…


Urs A. Meyer receives the 2019 Lifetime Achievement Award

Personalized medicine, a drug therapy tailored to the individual patient, is no longer a future vision on the horizon. One of the pioneers of this individualized therapy is Urs A. Meyer, Professor emeritus of Pharmacology.…


Therapy for muscular dystrophy: A new start-up at the Biozentrum

Congenital muscular dystrophy is a rare hereditary disease which cannot be cured. The more than 30 known forms of this neuromuscular disease differ in the type of genetic defect and in the severity of disease progression.…


Sleep-wake rhythm: Fish change our understanding of sleep regulation

Until recently, it was assumed that vertebrates share similar mechanisms controlling sleep behavior. That's why researchers have been using fish in the past 20 years as a model organism to study sleep and its regulation. Now…


Pregnancy remodels the brain: stem cells shape the sense of smell in mothers

Recognizing their offspring by smell ensures animal parents can nurture their own young. The research group led by Prof. Fiona Doetsch at the Biozentrum, University of Basel, has now demonstrated in mice that new nerve cells…


New glial cells discovered in the brain: Implications for brain repair

The brain is malleable well into adulthood. Brain plasticity is not only due to the formation of new nerve connections. Stem cells present in the adult brain also generate new nerve cells. For more than a hundred years,…


Inner “clockwork” sets the time for cell division in bacteria

The ability of pathogens to multiply in the host is crucial for the spread of infections. The speed of bacterial division greatly depends on the environmental conditions. Under unfavorable conditions, such as nutrient…


Bacteria have a sense of touch

Be it through mucosa or the intestinal lining, different tissues and surfaces of our body are entry gates for bacterial pathogens. The first few seconds - the moment of touch - are often critical for successful infections.…