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Discovery of a new antibiotic against resistant pathogens

The WHO calls the creeping and rapidly growing number of antibiotic-resistant bacteria a “silent pandemic”. The crisis is aggravated by the fact that hardly any new drugs have come onto the market in recent decades. Even…


Liver cancer: How liver cells go astray

The causes of liver cancer are manifold. In addition to metabolic disorders such as those associated with obesity, the main causes in the western world are infections with hepatitis C virus and high alcohol consumption.…


Lung organoids unveil secret: How pathogens infect human lung tissue

Earlier this year, the WHO published a list of twelve of the world’s most dangerous bacterial pathogens that are resistant to multiple antibiotics and pose a grave threat to human health. This list includes Pseudomonas…


More than just walking: a new role for core brain region

Even the mundane act of walking requires complex movements such as postural changes and the coordination of all four limbs. Scientists have known that the mesencephalic locomotor region, which is part of the midbrain, is…


Immune defense: How immune cells are activated

T lymphocyte immune cells protect our body against pathogens. Chemokine signaling molecules direct these T cells to the site of infection where they help to eliminate the invading pathogens. This process is mediated by…


Lab-on-a-chip for tracking single bacterial cells

It is hardly bigger than a matchbox and yet there is a laboratory en miniature on this chip. Single bacterial cells grow in about 2000 channels of a thousandth of a millimeter in diameter and can be individually studied in…


High-Speed Locomotion Neurons Found in the Brainstem

Think of you either taking a casual stroll on a sunny Sunday afternoon or running at full speed to catch a bus for work on Monday morning as two extremes. Both forms of locomotion entail a perfect interplay between arms and…


RNA molecules live short lives

RNA molecules are individual transcripts of the cell’s DNA. They transfer the genetic information of the DNA and provide a template for the production of proteins that regulate all the cell’s processes. The small carriers of…


Tracing the coronavirus with Nextstrain

Richard Neher has been conducting research at the Biozentrum since 2017. Yet never before has his opinion been so highly in demand as right now. Among scientists in Switzerland, he is one of the leading experts on the…


New vaccine concept tackles harmful bacteria in the intestine

The issue of intestinal bacteria is a complex one. On the one hand, we are dependent on the microorganisms because they are the ones that digest the food in our intestine. On the other hand, there are also numerous pathogens…