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OMERO Image Data Management

IMCF OMERO Image Management System OMERO is a biological image data management system designed to support the vast amount of imaging data a scientist may work with and to provide easy ways of accessing, showing and working…


Patricia Marini

Testimonial of Patricia Marini University of Basel, Switzerland, Research Group Dirk Bumann Where are you from and what are you studying? I’m from Rheinfelden in Germany, just over the border, and study molecular biology at…


Artificial Intelligence Tools shed light on millions of proteins

In the past years, AlphaFold has revolutionised protein science. This Artificial Intelligence (AI) tool was trained on protein data collected by life scientists for over 50 years, and is able to predict the 3D shape of…


A new layer of control in embryonic development

Genes provide the blueprint for life, determining when and where proteins are made. This process involves two key steps: transcription, from DNA to messenger mRNA (mRNA), and translation, where mRNA is decoded into proteins.…


Instruments & Services

Instruments & Services Welcome to the Biozentrum FACS Core Facility. We provide state-of-the-art flow cytometry instruments and support the users in their analysis and sorting needs. We offer scientific advice and customized…


Numerous genes important for muscle-nerve connection identified

Walking, breathing, or writing – these movements would not be possible without our muscles. The instructions are given by the nerves that communicate with the muscles through neuromuscular junctions. Damage to or loss of…


Survival trick: Pathogen taps iron source in immune cells

Our body keeps bacterial pathogens under control by restricting their access to essential nutrients such as iron. Iron is crucial for all living organisms. When bacteria are deprived of iron, they stop growing and…


GPS for proteins: Tracking the motions of cell receptors

G protein-coupled receptors are embedded in the cell membrane and transmit signals from the outside to the inside of the cell. Because of their vast diversity and crucial role in the body, GPCRs are targeted by many drugs,…


Perfect balance: How the brain fine-tunes its sensitivity

We are constantly exposed to a wide range of sensory stimuli, from loud noises to whispers. In order to efficiently process these diverse stimulus intensities, the brain needs to strike a balance in its responsiveness. An…


Everything in balance? How a molecular switch controls lipid metabolism

All organisms need energy to live. We get energy from various components of our food. Our body uses a part of this energy directly and stores the rest. While glucose serves as an immediately available energy source, fats are…