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How neuromuscular connections are maintained after nerve lesions

The protein complex mTORC1 promotes muscle growth and is important for the self-cleaning process of the muscle cells. The role of mTORC1 in skeletal muscle fibers in response to nerve injury has so far not been studied in…


Nanomachine keeps cellular power plants healthy

Every single cell of our body contains hundreds of tiny power plants, the mitochondria, which produce the energy required by the body, whether it be for walking, digesting or to ponder ideas. This inevitably generates…


Engineered enzymes: String pullers in cell communication

Cells are the building blocks of all living creatures. In order to form a complex organism and stay healthy, cells need to communicate with each other and integrate the response within themselves. A group of enzymes,…


Professor Views

Professor Views Prof. Silvia Arber explains how neurons control our movements All motor behaviors of the human body are controlled by neurons in the brain. Silvia Arber's team investigates how neurons build networks, how…


OMERO Image Data Management

IMCF OMERO Image Management System OMERO is a biological image data management system designed to support the vast amount of imaging data a scientist may work with and to provide easy ways of accessing, showing and working…


Patricia Marini

Testimonial of Patricia Marini University of Basel, Switzerland, Research Group Dirk Bumann Where are you from and what are you studying? I’m from Rheinfelden in Germany, just over the border, and study molecular biology at…


Artificial Intelligence Tools shed light on millions of proteins

In the past years, AlphaFold has revolutionised protein science. This Artificial Intelligence (AI) tool was trained on protein data collected by life scientists for over 50 years, and is able to predict the 3D shape of…


A new layer of control in embryonic development

Genes provide the blueprint for life, determining when and where proteins are made. This process involves two key steps: transcription, from DNA to messenger mRNA (mRNA), and translation, where mRNA is decoded into proteins.…


Numerous genes important for muscle-nerve connection identified

Walking, breathing, or writing – these movements would not be possible without our muscles. The instructions are given by the nerves that communicate with the muscles through neuromuscular junctions. Damage to or loss of…


Survival trick: Pathogen taps iron source in immune cells

Our body keeps bacterial pathogens under control by restricting their access to essential nutrients such as iron. Iron is crucial for all living organisms. When bacteria are deprived of iron, they stop growing and…