When pathogens infect an organism, the defense system immediately starts to fight the bacteria. To escape the patrolling immune cells, some bacteria invade and replicate inside host cells. However, the host has developed…
Since his time as a postdoctoral fellow at Harvard Medical School in Boston, Marek Basler has been fascinated by a tiny bacterial injection apparatus, the so-called type 6 secretion system (T6SS). This nanomachine works like…
Genetic information is protected in the cell nucleus by a membrane that contains numerous nuclear pores. These pores facilitate the traffic of proteins known as importins that deliver molecular cargoes between the nucleus…
Individual visual stimuli are not processed independently by our brain. Rather neurons exchange incoming information to form a coherent perceptual image from the myriad of visual details impinging on our eyes. How our visual…
Our brain generates new neurons throughout life. A diversity of stimuli promotes stem cells in their niche to form neurons that migrate to their place of action. In an animal model Prof. Fiona Doetsch’s team at the…
Testimonial of Dimitris Koufopoulos University of Aberdeen, Scotland, Research Group Christoph Handschin Where do you come from and what do you study? I am from Greece and study Biomedical Sciences at the University of…
With the revolutionary CRISPR/Cas technology, the DNA of living organisms can be precisely altered. Using a guide RNA that recognizes a specific DNA sequence, Cas9 protein is recruited to that sequence and cuts the DNA. This…
Testimonial Jordi Lagares Mir Instituto Químico de Sarriá (IQS), Research Group Christoph Dehio Where are you from and what do you study? I am from Besalú, a small medieval town in Catalonia, Spain. After completing primary…
In 1949, the Canadian psychologist Donald O. Hebb described that connections between neurons become stronger when the neurons are active at the same time, and that strengthened connections facilitate signal transmission. The…
The production of proteins is the most energy-consuming activity of cells. It needs to be tightly regulated, to ensure efficient use of cellular resources. Researchers led by Prof. Mihaela Zavolan at the Biozentrum have now…
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